Frederico Aires da Silva

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Assistant Professor and Principal Investigator

Faculty of Veterinary Medicine, University of Lisbon

Portugal

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About

Frederico Aires da Silva is an Assistant Professor and Principal Investigator at the Faculty of Veterinary Medicine, University of Lisbon, Portugal. His research areas encompass drug delivery systems, immunotherapy, and nanotechnology, with recent articles focusing on therapeutic targets in canine cancers and strategies for improving antibody drug conjugate efficiency. He investigates advanced methods such as phage display and characterizes interactions in viral proteins, contributing significantly to the fields of veterinary medicine and biopharmaceuticals.

Recent Grants

Grant: Close

SmartBox: Engineering the first generation of ROS responsive ADCs

Open Date: 2022-01-17

Close Date: 2025-01-16

Grant: Close

A novel tolerogenic liposome-based allergen immunotherapy for dogs in the horizon

Open Date: 2022-01-03

Close Date: 2023-07-02

Grant: Close

Development of potent and broadly neutralizing antibodies fragments for COVID-19 derived from domestic cats naturally infected with SARS-CoV-2

Open Date: 2022-01-02

Close Date: 2025-01-01

Grant: Close

TRIFECTA - Development of a novel trispecific antibody for the anticancer immune targeting of non-Hodgkin Lymphoma

Open Date: 2022-01-01

Close Date: 2023-06-30

Grant: Close

Development of immunoliposomes for specific targeting of non-Hodgkins lymphoma treatment

Open Date: 2020-01-01

Close Date: 2022-01-01

Articles (13)

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2020

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2020

Collaborators (15)

Vera Neves

Invited Assistant Professor

Universidade do Porto Faculdade de Medicina

PORTUGAL

Frederico Aires da Silva

Research Interests

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About

Recent Grants

Articles (13)

Rabbit derived VL single-domains as promising scaffolds to generate antibody–drug conjugates

Panobinostat-loaded folate targeted liposomes as a promising drug delivery system for treatment of canine B-cell lymphoma

Characterization of the canine CD20 as a therapeutic target for comparative passive immunotherapy

In Silico Characterization of African Swine Fever Virus Nucleoprotein p10 Interaction with DNA

In vivo Phage Display: A promising selection strategy for the improvement of antibody targeting and drug delivery properties

Occurrence of MDR1 1-delta mutation in herding dog breeds in Portugal

Loss of a-gal during primate evolution enhanced antibody-effector function and resistance to bacterial sepsis

Highly Specific Blood-Brain Barrier Transmigrating Single-Domain Antibodies Selected by an In Vivo Phage Display Screening

Diazaborines Are a Versatile Platform to Develop ROS‐Responsive Antibody Drug Conjugates**

Chemokine-Directed Tumor Microenvironment Modulation in Cancer Immunotherapy

Liposomes as Antibiotic Delivery Systems: A Promising Nanotechnological Strategy against Antimicrobial Resistance

A Prime-Boost Immunization Strategy with Vaccinia Virus Expressing Novel gp120 Envelope Glycoprotein from a CRF02_AG Isolate Elicits Cross-Clade Tier 2 HIV-1 Neutralizing Antibodies

Canine parvovirus: a predicting canine model for sepsis

Collaborators (15)

Vera Neves

Bruno L. Victor

Inês Bártolo

Jorge Vítor

Joana Amaral

Erida Gjini

Berta São Braz

Sílvia Almeida

Lurdes Gano

Sílvia Cardoso

Ana Rita Carlos

Solange Gil

Jorge Jesus Correia

Miguel Castanho

José Maria Marcelino

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