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Fuzheng Guo

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Professor

University of California, Davis

United States

Research Interests

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Recent Grants

Grant: Close

Serpina3n in demyelination and neuroinflammation

Open Date: 2024-07-01

Close Date: 2026-06-30

Grant: Close

Serpina3n/SERPINA3 in LPS-induced neonatal sepsis: liver-brain axis

Open Date: 2024-07-01

Close Date: 2026-06-30

Grant: Open

SOX2-regulated astrocyte homeostasis and pathophysiology

Open Date: 2024-01-01

Close Date: 2028-12-31

Grant: Close

Molecular interventions for periventricular leukomalacia

Open Date: 2023-01-01

Close Date: 2025-12-31

Grant: Open

The curious case of PARP1 in CNS myelin formation and repair

Open Date: 2022-07-01

Close Date: 2027-06-30

Articles (13)

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2026

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2024

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2023

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2023

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2023

Collaborators (7)

Bo Chen

Assistant Professor

University of Texas Medical Branch

UNITED STATES

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Jong Eun Lee

Yonsei University College of Medicine

SOUTH KOREA

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YAN WANG

Assistant Professor in Residence

University of California, Davis

UNITED STATES

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David Pleasure

Distinguished Professor

University of California, Davis

UNITED STATES

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Laura Borodinsky

Professor

University of California, Davis

UNITED STATES

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Wensheng Lin

Professor

University of Minnesota

UNITED STATES

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Jennifer McDonough

Associate Professor

Kent State University

UNITED STATES

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Fuzheng Guo

Research Interests

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Recent Grants

Articles (13)

Injury-transduced oligodendrocytes modulate neuroinflammation and glial activation in diseased and non-diseased central nervous system

Hepatokines and stellakines in liver and neurological diseases: The liver-brain axis

Crosstalk Between Oligodendrocyte Lineage Cells and CNS‐Resident and Peripheral Immune Cells Governs Demyelination and Remyelination in Multiple Sclerosis

Oligodendroglia as Active Immunomodulators in Demyelinating Diseases

Protocol for isolating and culturing microglia from the adult mouse brain using a magnetic-activated cell sorting system

A paradigm shift of SERPINA3N in neurobehavioral development and brain injury.

PAK1 regulates oligodendroglial proliferation and repopulation in homeostatic and demyelinating brain

Dispensable regulation of brain development and myelination by the immune‐related protein Serpina3n

Transcription factor 7‐like 2 (TCF7l2) regulates CNS myelination separating from its role in upstream oligodendrocyte differentiation

Regulation of CNS pathology by Serpina3n/SERPINA3: The knowns and the puzzles

Pathological Bergmann glia alterations and disrupted calcium dynamics in ataxic Canavan disease mice

TCF7l2, a nuclear marker that labels premyelinating oligodendrocytes and promotes oligodendroglial lineage progression

Cover Image, Volume 71, Issue 12

Collaborators (7)

Bo Chen

Jong Eun Lee

YAN WANG

David Pleasure

Laura Borodinsky

Wensheng Lin

Jennifer McDonough

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