Gabriel Piedrafita

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Universidad Complutense de Madrid

Spain

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Cell competition dynamics and clonal evolution during urothelial regeneration and carcinogenesis (uroCellDynasts)

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Articles (8)

Year:

2024

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2024

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2023

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2023

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2021

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2021

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2020

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2020

Collaborators (6)

Christoph Messner

Assistant Professor for Precision Proteomics

University of Zurich

SWITZERLAND

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Swee Hoe Ong

Wellcome Sanger Institute

UNITED KINGDOM

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Julian Griffin

University of Aberdeen

UNITED KINGDOM

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Charlotte King

Wellcome Sanger Institute

UNITED KINGDOM

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Maria P. Alcolea

Associate Professor

University of Cambridge

UNITED KINGDOM

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Osvaldo Graña Castro

Full-time professor

Universidad CEU San Pablo Facultad de Farmacia

SPAIN

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Gabriel Piedrafita

Research Interests

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Recent Grants

Articles (8)

Self-sustaining long-term 3D epithelioid cultures reveal drivers of clonal expansion in esophageal epithelium

Organismal metabolism regulates the expansion of oncogenic PIK3CA mutant clones in normal esophagus

Pseudoalignment tools as an efficient alternative to detect repeated transposable elements in scRNAseq data

Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth

Cysteine and iron accelerate the formation of ribose-5-phosphate, providing insights into the evolutionary origins of the metabolic network structure

Mutant clones in normal epithelium outcompete and eliminate emerging tumours

Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium

A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice

Collaborators (6)

Christoph Messner

Swee Hoe Ong

Julian Griffin

Charlotte King

Maria P. Alcolea

Osvaldo Graña Castro

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