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Gaël Roué

Has grant

Group Leader

Josep Carreras Leukaemia Research Institute

Spain

Research Interests

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Recent Grants

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Generation of a collection of fully annotated DLBCL 3D organotypic spheroids and PDX models for the preclinical testing of tumor-stroma crosstalk disruptors

Open Date: 2022-09-01

Close Date: 2025-08-01

Grant: Close

Evaluation of ON123300-based combination therapies in in vitro and in vivo models of mantle cell lymphoma with distinct sensitivities to BTK inhibitors

Open Date: 2022-09-01

Close Date: 2023-08-01

Grant: Close

Evaluation of the ROR1 inhibitor KAN571 in association with PI3Kδ-targeting therapy in preclinical models of B-cell non-Hodgkin lymphoma (B-NHL)

Open Date: 2021-01-01

Close Date: 2022-01-01

Grant: Close

Role of proteostasis in intratumoral heterogeneity and tumor-stroma crosstalk in aggressive B-cell lymphoma

Open Date: 2020-01-01

Close Date: 2021-01-01

Grant: Close

Modulation of lymphoid microenvironment by intrinsic protein homeostasis in aggressive B-cell lymphoma

Open Date: 2020-01-01

Close Date: 2021-01-01

Articles (13)

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2025

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2023

Collaborators (10)

Antoine Taly

CNRS Délégation Paris B

FRANCE

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Nathalie Bourgès-Abella

Professor, Histology

Ecole nationale vétérinaire de Toulouse

FRANCE

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Ignacio Campillo-Marcos

Senior Researcher

Institut de Recerca Sant Pau

SPAIN

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Julie Guillermet-Guibert

Chercheur

Université de Toulouse

FRANCE

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Nunzio Del Gaudio

ITALY

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Laura Mondragon Martinez

Junior Group Leader (Ramón y Cajal contract 2019)

Josep Carreras Leukaemia Research Institute

SPAIN

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Karine Reybier

Professor

Université de Toulouse

FRANCE

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Niklas Gebauer

University Hospital Schleswig-Holstein

GERMANY

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Caterina Mata Garcia

Head of the Single Cell Unit

Institut de Recerca Contra la Leucemia Josep Carreras

SPAIN

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Juliana Carvalho Santos

Josep Carreras Leukaemia Research Institute

SPAIN

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Gaël Roué

Research Interests

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Recent Grants

Articles (13)

Role of TRIM24 in the regulation of proteasome-autophagy crosstalk in bortezomib-resistant mantle cell lymphoma

METTL16-mediated inhibition of MXD4 promotes leukemia through activation of the MYC-MAX axis

CCR5-targeted allogeneic gamma-delta CD19 chimeric antigen receptor T cells for HIV-associated B cell-malignancy immunotherapy.

The role of miR-150-5p/E2F3/survivin axis in the pathogenesis of plasmablastic lymphoma and its therapeutic potential.

Single-cell Multiomics Analysis of Myelodysplastic Syndromes and Clinical Response to Hypomethylating Therapy.

Applying Molecular Modeling to the Design of Innovative, Non-Symmetrical CXCR4 Inhibitors with Potent Anticancer Activity

C/EBP & alpha; Confers Dependence to Fatty Acid Anabolic Pathways and Vulnerability to Lipid Oxidative Stress-Induced Ferroptosis in FLT3-Mutant Leukemia

Exportin 1‐mediated nuclear/cytoplasmic trafficking controls drug sensitivity of classical Hodgkin lymphoma

RHOA Therapeutic Targeting in Hematological Cancers

Editorial: The molecular landscape and promising therapeutic targets in aggressive B-cell non-Hodgkin lymphomas

Epigenetic targets in B- and T-cell lymphomas: latest developments

CARD11 gain of function upregulates BCL2A1 expression and promotes resistance to targeted therapies combination in B-cell lymphoma.

G protein-coupled receptor 183 mediates the sensitization of Burkitt lymphoma tumors to CD47 immune checkpoint blockade by anti-CD20/PI3Kδi dual therapy.

Collaborators (10)

Antoine Taly

Nathalie Bourgès-Abella

Ignacio Campillo-Marcos

Julie Guillermet-Guibert

Nunzio Del Gaudio

Laura Mondragon Martinez

Karine Reybier

Niklas Gebauer

Caterina Mata Garcia

Juliana Carvalho Santos

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