Gareth Brady

Assistant Professor of Vascular Biology

Trinity College Dublin

Ireland

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About

Gareth Brady is an Assistant Professor of Vascular Biology at Trinity College Dublin. His research areas include immune response to viral infections, particularly SARS-CoV-2, and the regulation of antiviral signaling pathways. Recent publications highlight his work on Type 1 interferon auto-antibodies in liver cirrhosis and metabolomic changes in immune cells. He is actively contributing to the understanding of immune mechanisms and their implications in health and disease.

Articles (13)

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2024

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2023

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2023

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2023

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2023

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2022

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2022

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2021

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2020

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2020

Collaborators (10)

Clíona Ní Cheallaigh

Associate Professor

Trinity College Dublin

IRELAND

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David Courtney

The Queen's University Belfast

UNITED KINGDOM

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Leonie Unterholzner

Senior Lecturer

University of Lancaster

UNITED KINGDOM

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Connor Bamford

The Queen's University Belfast

UNITED KINGDOM

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Mark Robinson

Assistant Professor

National University of Ireland, Maynooth

IRELAND

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Ann Leonard

Senior Clinical Lecturer

IRELAND

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Nollaig Bourke

Assistant Professor in Inflammaging

Trinity College Dublin

IRELAND

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Andrew Bowie

Professor of Innate Immunology

Trinity College Dublin

IRELAND

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Adrian Bracken

Professor

Trinity College Dublin

IRELAND

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Emma Connolly

Trinity College Dublin

IRELAND

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Gareth Brady

Research Interests

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Articles (13)

Type 1 interferon auto-antibodies are elevated in patients with decompensated liver cirrhosis

Molluscum Contagiosum Virus Protein MC008 Targets NF-κB Activation by Inhibiting Ubiquitination of NEMO

SARS-CoV-2 epidemiology, antibody dynamics, and neutralisation capacity in Irish healthcare workers in the era of booster COVID-19 vaccinations.

Optimal LC-MS metabolomic profiling reveals emergent changes to monocyte metabolism in response to lipopolysaccharide

Point of care detection of SARS-CoV-2 antibodies and neutralisation capacity—lateral flow immunoassay evaluation compared to commercial assay to inform potential role in therapeutic and surveillance practices

Bifurcation of signalling in human innate immune pathways to NF-kB and IRF family activation.

Regulation of IRF3 activation in human antiviral signaling pathways.

Previous SARS-CoV-2 Infection, Age, and Frailty Are Associated With 6-Month Vaccine-Induced Anti-Spike Antibody Titer in Nursing Home Residents.

Myeloid cell nuclear differentiation antigen controls the pathogen-stimulated type I interferon cascade in human monocytes by transcriptional regulation of IRF7.

Dynamic Assay for Profiling Anti-SARS-CoV-2 Antibodies and Their ACE2/Spike RBD Neutralization Capacity.

Study Protocol for DeCOmPRESS: Defining the Disease Course and Immune Profile of COVID-19 in the Immunosuppressed Patient

Poxviral Targeting of Interferon Regulatory Factor Activation.

Pathogenesis of ANCA-associated vasculitis: an emerging role for immunometabolism.

Collaborators (10)

Clíona Ní Cheallaigh

David Courtney

Leonie Unterholzner

Connor Bamford

Mark Robinson

Ann Leonard

Nollaig Bourke

Andrew Bowie

Adrian Bracken

Emma Connolly

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