Gaurav Sahay

Assistant Professor

Oregon State University

United States

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Dr. Gaurav Sahay serves as an Assistant Professor at Oregon State University in the United States. His research focuses on the development and application of lipid nanoparticles for gene delivery, particularly in the context of mRNA vaccines and therapeutics. Recent articles authored by Dr. Sahay explore innovative strategies for enhancing the efficacy and safety of non-viral delivery systems, including the use of saponins as adjuvants and engineering of lipid nanoparticles for targeted organ delivery.

Articles (16)

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2025

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2020

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2020

Collaborators (8)

Luis Martinez-Sobrido

Professor

Texas Biomedical Research Institute

UNITED STATES

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Daniel L. Marks

Oregon Health & Science University

UNITED STATES

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Kelvin MacDonald

Oregon Health & Science University

UNITED STATES

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Jeonghwan Kim

Assistant Professor

Yeungnam University College of Pharmacy

SOUTH KOREA

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Grace Su

Head of Operations for FreeGenes

Stanford University

UNITED STATES

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Yulia Eygeris

Oregon Health & Science University

UNITED STATES

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Oleh Taratula

UNITED STATES

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Kevin D. Welsher

Duke University

UNITED STATES

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Gaurav Sahay

Research Interests

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Articles (16)

Exploring the potential of saponins as adjuvants in lipid-nanoparticle-based mRNA vaccines

Synthesis of Ionizable Lipids for Gene Delivery to the Lung Using an Ugi Four Component Reaction

Microfluidic Platform Enables Shearless Aerosolization of Lipid Nanoparticles for mRNA Inhalation

Strategies for non-viral vectors targeting organs beyond the liver

A new era of targeting cystic fibrosis with non-viral delivery of genomic medicines

From Bench to Bedside: Implications of Lipid Nanoparticle Carrier Reactogenicity for Advancing Nucleic Acid Therapeutics

Lipid nanoparticles with PEG-variant surface modifications mediate genome editing in the mouse retina

Rapid Generation of Circulating and Mucosal Decoy Human ACE2 using mRNA Nanotherapeutics for the Potential Treatment of SARS‐CoV‐2

Engineering Lipid Nanoparticles for Enhanced Intracellular Delivery of mRNA through Inhalation

Chemistry of Lipid Nanoparticles for RNA Delivery

Leveraging Biological Buffers for Efficient Messenger RNA Delivery via Lipid Nanoparticles

Mining LTR-retrotransposon genes for mRNA delivery

Illuminating endosomal escape of polymorphic lipid nanoparticles that boost mRNA delivery

RNA-Based Therapeutics: Current Developments in Targeted Molecular Therapy of Triple-Negative Breast Cancer

Engineered mutant α-ENaC subunit mRNA delivered by lipid nanoparticles reduces amiloride currents in cystic fibrosis–based cell and mice models

The effects of PEGylation on LNP based mRNA delivery to the eye

Collaborators (8)

Luis Martinez-Sobrido

Daniel L. Marks

Kelvin MacDonald

Jeonghwan Kim

Grace Su

Yulia Eygeris

Oleh Taratula

Kevin D. Welsher

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