Gaurav Sharma

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Assistant Professor

University of Texas Southwestern Medical Center

United States

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About

Dr. Gaurav Sharma is an Assistant Professor at the University of Texas Southwestern Medical Center in the United States. His research focuses on cardiometabolic health, with recent publications exploring topics such as myocardial metabolic responses, hypothermic preservation of human donor hearts, and metabolomics-driven biomarker discovery for breast cancer. He is also investigating the neuroprotective properties of compounds like thymol and the therapeutic potential of quercetin against aflatoxin-related toxicity.

Recent Grants

Grant: Close

Prognostic Value of Hyperpolarized 13C MRI for Clinical Myocardial Viability

Open Date: 2023-07-01

Close Date: 2026-06-30

Grant: Close

Assessing Hibernating Myocardium with Hyperpolarized 13C MRI

Open Date: 2018-07-01

Close Date: 2020-06-01

Grant: Close

NMR spectroscopic analysis and anticancer evaluation of select ayurvedic polyherbal formulations

Open Date: 2010-06-01

Close Date: 2015-06-01

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2021

Collaborators (6)

Alexander Funk

University Hospital and Faculty of Medicine Carl Gustav Carus of TU Dresden

GERMANY

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Shivanand Pudakalakatti

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Deepak Parashar

Medical College of Wisconsin

UNITED STATES

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Shyam Chaurasia

Associate Professor

Medical College of Wisconsin

UNITED STATES

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Chalermchai Khemtong

Associate Professor

University of Florida College of Medicine

UNITED STATES

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Craig Malloy

Professor

University of Texas Southwestern Medical Center

UNITED STATES

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Gaurav Sharma

Research Interests

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About

Recent Grants

Articles (24)

Metabolic and transcriptomic insights into temperature controlled hypothermic preservation of human donor hearts

Deteriorated biomechanical properties of human hypertrophied septum in response to cardiomyocyte enlargement, overexpressed collagen, and disarrayed microstructures

Myocardial Metabolic Response to CABG Surgery as Assessed By Hyperpolarized Carbon-13 MRI

iPhone or Blackberry? The unsure future of ex vivo lung perfusion: A commentary on ex vivo lung perfusion national trends and posttransplant outcomes

Lycopene as a Therapeutic Agent against Aflatoxin B1-Related Toxicity: Mechanistic Insights and Future Directions

Thymol as a Potential Neuroprotective Agent: Mechanisms, Efficacy, and Future Prospects

Therapeutic detoxification of quercetin for aflatoxin B1-related toxicity: Roles of oxidative stress, inflammation, and metabolic enzymes

Recent advances associated with cardiometabolic remodeling in diabetes-induced heart failure

Metabolomics-Driven Biomarker Discovery for Breast Cancer Prognosis and Diagnosis

Hyperpolarized Carbon-13 Metabolic Imaging Detects Changes in Cardiac Mitochondrial Metabolism in Patients Before and After Coronary Artery Bypass Graft Surgery

Oxidation of hyperpolarized [1‐13C]pyruvate in isolated rat kidneys

Glycerol as a precursor for hepatic de novo glutathione synthesis in human liver

Enhancing Cancer Diagnosis with Real-Time Feedback: Tumor Metabolism through Hyperpolarized 1-13C Pyruvate MRSI

Neuroprotective Properties of Berberine: Molecular Mechanisms and Clinical Implications

Fatty Acid Oxidation Decreases Independently Of Up-regulated Glucose Utilization In The Setting Of Elevated Afterload

Metabolic Analysis of Human Hearts Preserved with a Novel Hypothermic Perfusion System

Metabolic Indicators in Donor Hearts Following Conventional and Temperature Controlled Storage

Aflatoxin B1 Toxicity and Protective Effects of Curcumin: Molecular Mechanisms and Clinical Implications

Quercetin Attenuates Quinocetone-Induced Cell Apoptosis In Vitro by Activating the P38/Nrf2/HO-1 Pathway and Inhibiting the ROS/Mitochondrial Apoptotic Pathway

274-OR: The Malic Enzyme-1 Links Pyruvate Carboxylase–Mediated Anaplerosis to Redox State in Liver

Imaging β-Cell Function Using a Zinc-Responsive MRI Contrast Agent May Identify First Responder Islets

Imaging beta-Cell Function Using a Zinc-Responsive MRI Contrast Agent May Identify First Responder Islets

Co-Polarized [1-13C]Pyruvate and [1,3-13C2]Acetoacetate Provide a Simultaneous View of Cytosolic and Mitochondrial Redox in a Single Experiment

PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart

Collaborators (6)

Alexander Funk

Shivanand Pudakalakatti

Deepak Parashar

Shyam Chaurasia

Chalermchai Khemtong

Craig Malloy

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