George Aslanidi

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Professor

University of Minnesota

United States

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About

George Aslanidi is a Professor at the University of Minnesota, USA. His research focuses on adeno-associated virus (AAV) vector development and applications, including vector purification, targeted delivery, and the immune response to AAV-mediated vaccines. His recent work includes exploring the efficiency of AAV vectors in treating various conditions and enhancing gene delivery mechanisms.

Recent Grants

Grant: Close

Optimized Production and Validation of Rationally Designed AAV Vectors for Cockayne Syndrome Gene Therapy

Open Date: 2021-09-01

Close Date: 2024-08-31

Grant: Close

Mechanism of high-efficiency transduction of hepatocytes by optimized AAV vectors

Open Date: 2017-01-01

Close Date: 2021-12-31

Articles (12)

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2025

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2025

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2024

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2024

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2023

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2023

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2023

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2023

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2023

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2020

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2020

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2020

Collaborators (6)

Christina Pacak

University of Minnesota

UNITED STATES

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Melanie Graham

University of Minnesota

UNITED STATES

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Neeraj Sharma

Assistant Professor

Johns Hopkins University School of Medicine

UNITED STATES

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Wei‐Shou Hu

UNITED STATES

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Wendy Gordon

University of Minnesota

UNITED STATES

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Daniel Schmidt

University of Minnesota

UNITED STATES

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George Aslanidi

Research Interests

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Contact this professor

About

Recent Grants

Articles (12)

A synthetic platform for developing recombinant adeno-associated virus type 8 producer cell lines

Consecutive Affinity and Ion-Exchange Chromatography for AAV9 Vectors Purification

AAV-DJ is superior to AAV9 for targeting brain and spinal cord, and de-targeting liver across multiple delivery routes in mice

Insights in AAV-mediated antigen-specific immunity and a strategy for AAV vaccine dose reduction through AAV-extracellular vesicle association

Multiplexing AAV Serotype-Specific Neutralizing Antibodies in Preclinical Animal Models and Humans

Tumor antigen-loaded AAV vaccine drives protective immunity in a melanoma animal model

Multiparametric domain insertional profiling of adeno-associated virus VP1

Bioengineered Hybrid Rep 2/6 Gene Improves Encapsulation of a Single-Stranded Expression Cassette into AAV6 Vectors

Extracellular vesicles enhance pulmonary transduction of stably associated adeno-associated virus following intratracheal administration

Intra-tracheal delivery of AAV6 vectors results in sustained transduction in murine lungs without genomic integration

Modifiers of Adeno-Associated Virus-Mediated Gene Expression in Implication for Serotype-Universal Neutralizing Antibody Assay

Neutrophil elastase promotes macrophage cell adhesion and cytokine production through the integrin-Src kinases pathway

Collaborators (6)

Christina Pacak

Melanie Graham

Neeraj Sharma

Wei‐Shou Hu

Wendy Gordon

Daniel Schmidt

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