Georgina Aldridge

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Assistant Professor

Iowa State University

United States

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About

Georgina Aldridge is an Assistant Professor at the University of Iowa, located in the United States. Her research areas encompass neurodegenerative diseases, with a focus on alpha-synuclein pathology and its implications in conditions such as Parkinson's disease and Alzheimer's disease. Recent publications reflect her work on the mechanisms of dementia, including the effects of medication on cognitive symptoms and the role of tau pathology in neurodegenerative processes.

Recent Grants

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Cortical Mechanisms in Lewy Body Dementia

Open Date: 2018-09-18

Close Date: 2023-06-30

Articles (13)

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2024

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2021

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2021

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The University of Iowa

UNITED STATES

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Georgina Aldridge

Research Interests

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About

Recent Grants

Articles (13)

Association of Terazosin, Doxazosin, or Alfuzosin Use and Risk of Dementia With Lewy Bodies in Men

Enhanced Spine Stability and Survival Lead to Increases in Dendritic Spine Density as an Early Response to Local Alpha-Synuclein Overexpression in Mouse Prefrontal Cortex

Tau pathology in the dorsal raphe may be a prodromal indicator of Alzheimer’s disease

Skin Biopsy Detection of Phosphorylated α-Synuclein in Patients With Synucleinopathies.

Alpha-Synuclein Pre-Formed Fibrils Injected into Prefrontal Cortex Primarily Spread to Cortical and Subcortical Structures

Mice Expressing A53T/A30P Mutant Alpha-Synuclein in Dopamine Neurons Do Not Display Behavioral Deficits

Normal Pressure Hydrocephalus in Adult Mice Causes Gait Impairment, Cognitive Deficits, and Urinary Frequency with Incontinence

Glycolysis-enhancing α<sub>1</sub>-adrenergic antagonists modify cognitive symptoms related to Parkinson's disease.

BoutonNet: an automatic method to detect anterogradely labeled presynaptic boutons in brain tissue sections

Stay or go? Neuronal activity in medial frontal cortex during a voluntary tactile preference task in head-fixed mice

COVID-19 Case Fatality and Alzheimer's Disease

Coronavirus Disease 2019 Case Fatality and Parkinson's Disease

Local cortical overexpression of human wild-type alpha-synuclein leads to increased dendritic spine density in mouse

Collaborators (6)

Kanza Khan

Nikolaus McFarland

Jacob Simmering

Kimberly Fiock

Joel Geerling

Qiang Zhang

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