Ghislain Opdenakker

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Emeritus Full Professor in service

Katholieke Universiteit Leuven

Belgium

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About

Ghislain Opdenakker is an Emeritus Full Professor at Katholieke Universiteit Leuven (KU Leuven) in Belgium. His research primarily focuses on the interplay between inflammation and various disorders, including diabetes and autoimmune diseases, as evidenced by his recent articles on drug-resistance mutations, endothelial function, and the role of macrophage transition in proliferative disorders. He has contributed significantly to the understanding of glycoprotein interactions and the implications for precision medicine in conditions such as arthritis and uveitis.

Recent Grants

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Articles (15)

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2025

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2020

Collaborators (6)

Wiebke Möbius

Head of the Electron Microscopy Core Unit, City Campus

Max Planck Institute for Multidisciplinary Sciences

GERMANY

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Christine Stadelmann

GERMANY

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Sofie Struyf

Katholieke Universiteit Leuven Rega Institute for Medical Research

BELGIUM

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Saleh A. Al-Obeidan

SAUDI ARABIA

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Mohd Imtiaz Nawaz

SAUDI ARABIA

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Celso Reis

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto

PORTUGAL

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Ghislain Opdenakker

Research Interests

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Articles (15)

Primary HSV-2 Infection in an Immunocompromised Patient Reveals High Diversity of Drug-Resistance Mutations in the Viral DNA Polymerase

Functional Interactions Between Recombinant Serum Amyloid A1 (SAA1) and Chemokines in Leukocyte Recruitment

ADAMTS13 Improves Endothelial Function and Reduces Inflammation in Diabetic Retinopathy

Macrophage-Myofibroblast Transition Contributes to Myofibroblast Formation in Proliferative Vitreoretinal Disorders

Matrix metalloproteinases in arthritis: towards precision medicine

Therapeutic window of opportunity in the acute uveitic phase of Vogt–Koyanagi–Harada disease: Prevention of late autoimmune complications by early intervention

CD40 Ligand–CD40 Interaction Is an Intermediary between Inflammation and Angiogenesis in Proliferative Diabetic Retinopathy

Autoantigen characterization in the lower esophageal sphincter muscle of patients with achalasia

Meeting report on 14th Jenner Glycobiology and Medicine Symposium: glycobiology in immunology, medicine, and clinical practice

How to place the duality of specific MMP-9 inhibition for treatment of inflammatory bowel diseases into clinical opportunities?

Interferons and other cytokines, genetics and beyond in COVID-19 and autoimmunity

Blood-brain barrier resealing in neuromyelitis optica occurs independently of astrocyte regeneration

Soluble cytokine receptor levels in aqueous humour of patients with specific autoimmune uveitic entities: sCD30 is a biomarker of granulomatous uveitis

Homotrimeric MMP-9 is an active hitchhiker on alpha-2-macroglobulin partially escaping protease inhibition and internalization through LRP-1

Neutrophils: Underestimated Players in the Pathogenesis of Multiple Sclerosis (MS)

Collaborators (6)

Wiebke Möbius

Christine Stadelmann

Sofie Struyf

Saleh A. Al-Obeidan

Mohd Imtiaz Nawaz

Celso Reis

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