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Giacomo Cavalli

Has grant

Research Director

CNRS Délégation Languedoc-Roussillon

France

Research Interests

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Recent Grants

Grant: Open

Deciphering the role of regulatory factors driving epigenetic inheritance of alternative chromatin states

Open Date: 2024-11-01

Close Date: 2029-10-01

Grant: Close

The fate of functional chromatin states through mitosis: a single-cell analysis

Open Date: 2021-05-01

Close Date: 2024-04-30

Grant: Close

3DEpi

Open Date: 2018-11-01

Close Date: 2023-10-01

Grant: Close

Multiscale Complex Genomics (MuG)

Open Date: 2015-11-01

Close Date: 2018-10-01

Grant: Close

Epigenetic regulation of development: towards a predictive mathematical modeling of three dimensional genome folding and cellular memory – EpiDevoMath

Open Date: 2015-09-22

Close Date: 2018-09-21

Articles (20)

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Collaborators (10)

Marta Coronado-Zamora

Lecturer

Universitat Autònoma de Barcelona (UAB)

SPAIN

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Raúl F. Pérez

Associate professor

Universidad Complutense de Madrid

SPAIN

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thierry fest

university hospital of Rennes

FRANCE

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Lucas Waltzer

Group leader

Université Clermont Auvergne

FRANCE

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Anne-marie martinez

Full Professor (PRCE)

University of Montpellier

FRANCE

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Caroline BRET

Maître de Conférence des Universités-Praticien Hospitalier, head of the Flow Cytometry Laboratory

FRANCE

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Michael Elgart

Principal Investigator

Tel Aviv University

ISRAEL

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Josefa Gonzalez

CSIC Research Scientist

CSIC

SPAIN

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yoan Renaud

CNRS Délégation Rhône-Auvergne

FRANCE

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Bernd Schuettengruber

INSERM Délégation régionale Languedoc-Roussillon

FRANCE

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Giacomo Cavalli

Research Interests

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Recent Grants

Articles (20)

Looping specificity of Polycomb response elements requires GAF and a combination of looping factors that could form a code

A scaffolding element rewires local 3D chromatin architecture during differentiation

Loss of SUMOylation drives aberrant PRC1 clustering and 3D genome rewiring independent of H3K27me3

PRC1 nanoglobules organize Hox chromatin during Drosophila embryogenesis

Transient histone deacetylase inhibition induces cellular memory of gene expression and 3D genome folding

3D genome folding in epigenetic regulation and cellular memory

A possible role for epigenetics in cancer initiation

A mechanistic basis for genetic assimilation in natural fly populations

Determining the functional relationship between epigenetic and physical chromatin domains in Drosophila

Interchromosomal contacts between regulatory regions trigger stable transgenerational epigenetic inheritance in Drosophila

Oligopaint FISH to Study Chromosomal Architecture and Structural Variations

Drosophila TET acts with PRC1 to activate gene expression independently of its catalytic activity

Integrative single-cell chromatin and transcriptome analysis of human plasma cell differentiation

A PRE loop at the dac locus acts as a topological chromatin structure that restricts and specifies enhancer–promoter communication

Sustained inactivation of the Polycomb PRC1 complex induces DNA repair defects and genomic instability in epigenetic tumors.

Transient loss of Polycomb components induces an epigenetic cancer fate.

Organ transformation by environmental disruption of protein integrity and epigenetic memory in Drosophila

Evolution and function of chromatin domains across the tree of life

Phase separation and inheritance of repressive chromatin domains

The Density of Regulatory Information Is a Major Determinant of Evolutionary Constraint on Noncoding DNA in Drosophila

Collaborators (10)

Marta Coronado-Zamora

Raúl F. Pérez

thierry fest

Lucas Waltzer

Anne-marie martinez

Caroline BRET

Michael Elgart

Josefa Gonzalez

yoan Renaud

Bernd Schuettengruber

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