Gianluca Sbardella

Professore Ordinario

Università degli Studi di Napoli Federico II

Italy

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About

Gianluca Sbardella is a Professore Ordinario at the Università degli Studi di Salerno, Italy. His research focuses on medicinal chemistry and chemical biology, with recent publications highlighting topics such as selective inhibitors of lysine acetyltransferases and benzodiazepine derivatives as bromodomain inhibitors. He also explores age-related cognitive effects in Alzheimer's disease models and the development of non-covalent inhibitors for cancer treatment.

Articles (10)

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2021

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2021

Collaborators (7)

Monica Viviano

University of Salerno

ITALY

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Jean CAVARELLI

Professor

FRANCE

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Stefan A. Laufer

Eberhard Karls Universität Tübingen

GERMANY

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Giulia Iannelli

Universität Wien

AUSTRIA

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Anders Bach

Københavns Universitet

DENMARK

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Ciro Milite

Associate Professor

Università degli Studi di Napoli Federico II

ITALY

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stefano tomassi

Associate Professor

Link Campus University

ITALY

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Gianluca Sbardella

Research Interests

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Articles (10)

The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Hit Generation

First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8.

EFMC: Trends in Medicinal Chemistry and Chemical Biology.

Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction–Reconstruction and Fragment-Growing Approach

Discovery of Benzo[d]imidazole-6-sulfonamides as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain.

Age-dependent attenuation of spatial memory deficits by the histone acetyltransferase p300/CBP-associated factor (PCAF) in 3xTG Alzheimer's disease mice

Lysine methyltransferase inhibitors: where we are now

Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models

Lysine methyltransferase inhibitors: where we are now

The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Phenotypic Drug Discovery

Collaborators (7)

Monica Viviano

Jean CAVARELLI

Stefan A. Laufer

Giulia Iannelli

Anders Bach

Ciro Milite

stefano tomassi

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