Giovanni Botten

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United States

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Deconvolution of Enhancer Function and Composition During Cardiac Differentiation

Open Date: 2021-04-01

Close Date: 2022-09-26

Articles (10)

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2024

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2023

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2023

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2023

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2023

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2021

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2021

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2021

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2021

Collaborators (7)

Jian Xu

University of Texas Southwestern Medical Center

UNITED STATES

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Wenfeng An

Professor

South Dakota State University

UNITED STATES

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Nathalie Droin

Inserm u1183

FRANCE

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Yi-Tsang Lee

La Jolla Institute for Immunology

UNITED STATES

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Peter Ly

Assistant Professor

University of Texas Southwestern Medical Center

UNITED STATES

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Marcel Mettlen

Associate Professor and Director of the Quantitative Light Microscopy Core

University of Texas Southwestern Medical Center

UNITED STATES

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John M. Abrams

Professor

University of Texas Southwestern Medical Center

UNITED STATES

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Giovanni Botten

Research Interests

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Recent Grants

Articles (10)

T/myeloid mixed phenotype acute leukaemia harbouring TLX3::BCL11B with TLX3 activation.

Structural Variation Cooperates with Permissive Chromatin to Control Enhancer Hijacking-Mediated Oncogenic Transcription

Light-activated macromolecular phase separation modulates transcription by reconfiguring chromatin interactions

Pathogenic human variant that dislocates GATA2 zinc fingers disrupts hematopoietic gene expression and signaling networks.

Pathogenic human variant that dislocates GATA2 zinc fingers disrupts hematopoietic gene expression and signaling networks

Dissecting Locus-Specific Chromatin Interactions by CRISPR CAPTURE.

Silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia.

Inner nuclear protein Matrin-3 coordinates cell differentiation by stabilizing chromatin architecture.

Detection of viral gene expression in risk-stratified biopsies reveals no active HPV in cutaneous squamous cell carcinoma.

Mixed Phenotype Acute Leukemia, B/Myeloid (Bilineal and Biphenotypic), With t(2;22)(q35;q12);EWSR1-FEV.

Collaborators (7)

Jian Xu

Wenfeng An

Nathalie Droin

Yi-Tsang Lee

Peter Ly

Marcel Mettlen

John M. Abrams

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