Giovanni Germano

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Candiolo Cancer Institute, FPO-IRCCS

Italy

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Recent Grants

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The impact of immune-mediated surveillance on cancer cells with mismatch repair alterations

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The impact of the non-coding genome on response to immune based therapies in gastrointestinal cancers

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Articles (9)

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2024

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2024

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2023

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2023

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2022

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2021

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2021

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2021

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2020

Collaborators (10)

Andrea Sartore-Bianchi

Associate Professor

Università degli Studi di Torino

ITALY

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Francesco Sassi

Candiolo Cancer Institute, FPO-IRCCS

ITALY

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SALVATORE SIENA

Full Professor of Medical Oncology

Università degli Studi di Torino

ITALY

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Enrico Berrino

Università degli Studi di Foggia Dipartimento di Scienze Mediche e Chirurgiche

ITALY

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Valeria Pessei

Candiolo Cancer Institute

ITALY

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ALICE BARTOLINI

Candiolo Cancer Institute, FPO-IRCCS

ITALY

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Federica Di Nicolantonio

ITALY

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Alberto Bardelli

ITALY

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Nicola Personeni

Humanitas University

ITALY

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patrizia stoitzner

Head of Laboratory

Medical University of Innsbruck

AUSTRIA

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Giovanni Germano

Research Interests

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Recent Grants

Articles (9)

Dendritic cell-targeted therapy expands CD8 T cell responses to bona-fide neoantigens in lung tumors.

Non-canonical antigens are the largest fraction of peptides presented by MHC class I in mismatch repair deficient murine colorectal cancer.

Genetic and pharmacological modulation of DNA mismatch repair heterogeneous tumors promotes immune surveillance

Unique Patterns of Heterogeneous Mismatch Repair Protein Expression in Colorectal Cancer Unveil Different Degrees of Tumor Mutational Burden and Distinct Tumor Microenvironment Features

Temozolomide Treatment Alters Mismatch Repair and Boosts Mutational Burden in Tumor and Blood of Colorectal Cancer Patients.

T Cells Expressing Receptor Recombination/Revision Machinery Are Detected in the Tumor Microenvironment and Expanded in Genomically Over-unstable Models.

Mechanisms of Immune Escape and Resistance to Checkpoint Inhibitor Therapies in Mismatch Repair Deficient Metastatic Colorectal Cancers

CD4 T Cell-Dependent Rejection of Beta-2 Microglobulin Null Mismatch Repair-Deficient Tumors.

High-dose vitamin C enhances cancer immunotherapy.

Collaborators (10)

Andrea Sartore-Bianchi

Francesco Sassi

SALVATORE SIENA

Enrico Berrino

Valeria Pessei

ALICE BARTOLINI

Federica Di Nicolantonio

Alberto Bardelli

Nicola Personeni

patrizia stoitzner

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