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Giovanni Nigita

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Assistant Professor

The Ohio State University Wexner Medical Center

United States

Research Interests

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Recent Grants

Grant: Open

HERV loci as biomarkers/targets in osimertinib-resistant EGFRmutant NSCLC.

Open Date: 2026-07-01

Close Date: 2028-06-01

Grant: Close

TRAP1: a novel potential therapeutic target for DDLPS?

Open Date: 2024-07-01

Close Date: 2026-01-01

Grant: Close

isomiRGate: a comprehensive gateway for studying the canonical and modified microRNAomes in Cancer

Open Date: 2024-06-01

Close Date: 2026-05-01

Grant: Close

The role of non-coding RNA editing in MET signaling in NSCLC

Open Date: 2022-07-01

Close Date: 2024-06-01

Grant: Close

Computational Analysis of RNA editing and its implication in Cancer

Open Date: 2014-04-01

Close Date: 2015-04-01

Articles (18)

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Collaborators (9)

Alfredo Pulvirenti

Associate Professor of Computer Science

University of Catania

ITALY

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Joal D. Beane

Ohio State University

UNITED STATES

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MICHELA SAVIANA

Virginia Commonwealth University

UNITED STATES

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Andrea Vecchione

ITALY

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Valerie Grignol

Assistant Professor of Surgery

The Ohio State University Wexner Medical Center

UNITED STATES

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Carlo M. Croce

Distinguished University Professor

Ohio State University

UNITED STATES

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Eloisa Jantus Lewintre

Profesora titular

Universitat Politècnica de València

SPAIN

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David R. Gandara

Co-Director, Center for Experimental Therapeutics in Cancer

University of California Davis Comprehensive Cancer Center

UNITED STATES

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Lalit Sehgal

Associate Professor

Ohio State University

UNITED STATES

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Giovanni Nigita

Research Interests

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Recent Grants

Articles (18)

Protocol for analyzing tRNA-derived ncRNAs from small RNA-seq data using tRFUniverse functional analyses.

International society of liquid biopsy (ISLB) perspective on minimal requirements for ctDNA testing in solid tumors.

ncRNA Editing: Functional Characterization and Computational Resources.

tRFUniverse: A comprehensive resource for the interactive analyses of tRNA-derived ncRNAs in human cancer

Nutrient restriction-activated Fra-2 promotes tumor progression via IGF1R in miR-15a downmodulated pancreatic ductal adenocarcinoma

Oncogenic Functions of Alternatively Spliced MDM2-ALT2 Isoform in Retroperitoneal Liposarcoma

Extracellular Vesicle - MDM2-DNA as a Potential Liquid Biopsy Biomarker for Disease Identification in Retroperitoneal Liposarcoma.

Poly(A)-specific RNase (PARN) generates and regulates miR-125a-5p 3'-isoforms, displaying an altered expression in breast cancer.

The MITF/mir-579-3p regulatory axis dictates BRAF-mutated melanoma cell fate in response to MAPK inhibitors.

Small Non-Coding RNAs in Soft-Tissue Sarcomas: State of the Art and Future Directions

A plasma miRNA-based classifier for small cell lung cancer diagnosis

A-to-I edited miR-411-5p targets MET and promotes TKI response in NSCLC-resistant cells

Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4.

Expression signature of human endogenous retroviruses in chronic lymphocytic leukemia.

Genetically modified IL2 bone-marrow-derived myeloid cells reprogram the glioma immunosuppressive tumor microenvironment.

Editorial: RNA modifications and epitranscriptomics, Volume II.

Single-cell RNA sequencing reveals immunosuppressive myeloid cell diversity during malignant progression in a murine model of glioma.

Role of the miR-301a/Fra-2/GLIPR1 axis in lung cancer cisplatin resistance.

Collaborators (9)

Alfredo Pulvirenti

Joal D. Beane

MICHELA SAVIANA

Andrea Vecchione

Valerie Grignol

Carlo M. Croce

Eloisa Jantus Lewintre

David R. Gandara

Lalit Sehgal

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