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Glaucio Monteiro Ferreira

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Associate Researcher (FAPESP grant: 2023/15933-4)

University of Sao Paulo

Brazil

Research Interests

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Professors in Biochemistry

Recent Grants

Grant: Open

Molecular Modeling Drug Screening Platform (MMDSP): a model preclinical and molecular insights for the development of new antilipidemic drug targeting PCSK9

Open Date: 2026-01-01

Close Date: 2030-12-01

Grant: Close

Development of new drugs based on the structure of essential proteins for cholesterol synthesis and metabolism, integrating genetic studies and molecular modeling of dyslipidemic patients

Open Date: 2021-12-01

Close Date: 2024-12-01

Grant: Close

Novel HMG-CoA reductase inhibitors development by integrating dyslipidemic patients’ genetic studies and molecular modelling

Open Date: 2020-03-01

Close Date: 2021-03-01

Grant: Close

Search of new drugs against Hypercholesterolemia, based on genetic and epigenetic markers specific to the Brazilian population

Open Date: 2019-05-01

Close Date: 2021-12-01

Articles (19)

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2023

Collaborators (9)

Graham Moran

Professor

Loyola University Chicago

UNITED STATES

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Roberto Parise Filho

Associate Professor

University of Sao Paulo

BRAZIL

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Flavio Emery

Associate Professor

University of Sao Paulo

BRAZIL

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Michel Naslavsky

Professor Doctor

University of Sao Paulo

BRAZIL

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Patricia Moriel

Professor

University of Campinas

BRAZIL

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Peter Doubleday

ETH Zürich

SWITZERLAND

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Thales Kronenberger

GERMANY

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Dali Liu

Professor

Loyola University Chicago

UNITED STATES

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Antti Poso

Professor at University of Eastern Finland

University of Eastern Finland

FINLAND

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Glaucio Monteiro Ferreira

Research Interests

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Recent Grants

Articles (19)

Antiviral Potential of 3,4-Dimethoxychalcone Against SARS-CoV-2: A Promising Candidate

Mapping the APOE structurally on missense variants in elderly Brazilians

Druggable Targets in Zika Virus: A Systematic Review of Therapeutic Opportunities in Brazil

Correction to “Design, Synthesis, and Mechanistic Studies of (R)-3-Amino-5,5-difluorocyclohex-1-ene-1-carboxylic Acid as an Inactivator of Human Ornithine Aminotransferase”

Design, Synthesis, and Mechanistic Studies of (R)-3-Amino-5,5-difluorocyclohex-1-ene-1-carboxylic Acid as an Inactivator of Human Ornithine Aminotransferase

Predicted deleterious variants in ABCA1, LPL, LPA and KIF6 are associated with statin response and adverse events in patients with familial hypercholesterolemia and disturb protein structure and stability

Aryl-isoquinoline as a Potential Scaffold for Novel Antitumor Agents against Glioblastoma Cells

Effects of LDLR variants rs5928, rs750518671 and rs879254797 on protein structure and functional activity in HepG2 cells transfected with CRISPR/Cas9 constructs

Correction to “Rational Design, Synthesis, and Mechanism of (3S,4R)-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation Strategy for Selectivity of Human Ornithine Aminotransferase over GABA Aminotransferase”

Structural and Mechanistic Basis for the Inactivation of Human Ornithine Aminotransferase by (3S,4S)-3-Amino-4-fluorocyclopentenecarboxylic Acid

Trypanosoma cruzi Sirtuin 2 as a Relevant Druggable Target: New Inhibitors Developed by Computer-Aided Drug Design

Dynamics of the personalities of PCSK9 on missense variants (rs505151 and rs562556) from elderly cohort studies in Brazil

Identification of pathogenic variants in the Brazilian cohort with Familial hypercholesterolemia using exon-targeted gene sequencing

Innovative Microemulsion Loaded with Unusual Dimeric Flavonoids from Fridericia platyphylla (Cham.) L.G. Lohmann Roots

Exploring the dark side of tertiary and quaternary structure dynamics in <i>Mtb</i> FBPaseII

Association of occupational exposure to pesticides with overweight in farmers in Southern Brazil

Covalent Inhibitors for Neglected Diseases: An Exploration of Novel Therapeutic Options

Exploring the conformational dynamics of the CRD4: a model for receptor lysosomal activity shifts in search of 'sweet’ and ‘sour’ states

Correction to: Innovative Microemulsion Loaded with Unusual Dimeric Flavonoids from Fridericia platyphylla (Cham.) L.G. Lohmann Roots (AAPS PharmSciTech, (2023), 24, 8, (212), 10.1208/s12249-023-02655-z)

Collaborators (9)

Graham Moran

Roberto Parise Filho

Flavio Emery

Michel Naslavsky

Patricia Moriel

Peter Doubleday

Thales Kronenberger

Dali Liu

Antti Poso

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