Glenn Micalizio

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New Hampshire Professor

Dartmouth College

United States

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About

Glenn Micalizio is a Professor at Dartmouth College in New Hampshire, USA. His research focuses on synthetic organic chemistry, particularly in the areas of steroid synthesis and the development of pharmaceutical leads from natural products. Recent articles authored by Professor Micalizio explore topics such as estrogen receptor activity, glucocorticoid receptor modulation, and the asymmetric de novo synthesis of complex terpenoid structures.

Recent Grants

Grant: Close

Metallacycle-mediated coupling in stereoselective synthesis

Open Date: 2020-01-01

Close Date: 2024-12-31

Grant: Close

Studies in Natural Product Synthesis

Open Date: 2017-08-01

Close Date: 2021-05-31

Grant: Close

Synthesis and Validation of Novel Cyclin Dependent Kinase Inhibitors as Potential Anticancer Drugs

Open Date: 2016-01-01

Close Date:

Grant: Close

Synthesis and Anticancer Activity of Novel Pectenotoxins

Open Date: 2015-01-01

Close Date:

Grant: Close

A Biomimetic Approach to Molecular Diversity as a Foundation to Small Molecule Ligand Discovery

Open Date: 2011-01-01

Close Date:

Articles (14)

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2025

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2024

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2024

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2024

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2024

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2022

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2022

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2022

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2022

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2022

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2021

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2021

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2020

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2020

Collaborators (3)

Christopher Coss

Associate Professor

Ohio State University

UNITED STATES

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Matthew Hayes

Research Assistant Professor

University of Florida

UNITED STATES

View details

Thomas P. Burris

UNITED STATES

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Glenn Micalizio

Research Interests

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About

Recent Grants

Articles (14)

An Estrogen Receptor β Agonist with AR Antagonist Activity from a Modern Asymmetric De Novo Steroid Synthesis

Merging Natural Product Structures with Pharmaceutical Leads: Unnatural Enantiomers of Estranes as Glucocorticoid Receptor Modulators That Suppress TNF-α and IL-6 Release

Function-Oriented Synthesis of Pentacyclic Triterpenoids and Discovery of an ent-Estrane as a Natural Product-Inspired Androgen Receptor Antagonist

From Functional Fatty Acids to Potent and Selective Natural-Product-Inspired Mimetics via Conformational Profiling.

Progress Toward the Asymmetric De Novo Synthesis of Limonoids

Toward the Asymmetric de Novo Synthesis of Lanostanes: Construction of 7,11-Dideoxy-Δ5-lucidadone H

Toward the Asymmetric Synthesis of Cardenolides and Related Steroidal Systems: syn-SN2′ of Organometallics with C14–C17 Vinylepoxides

Progress toward the De Novo Asymmetric Synthesis of Euphanes

Asymmetric De Novo Synthesis of a Cucurbitane Triterpenoid: Total Synthesis of Octanorcucurbitacin B

General Enantioselective and Stereochemically Divergent Four-Stage Approach to Fused Tetracyclic Terpenoid Systems

An Enantiodefined Conformationally Constrained Fatty Acid Mimetic and Potent Inhibitor of ToxT

From an ent-Estrane, through a nat-Androstane, to the Total Synthesis of the Marine-Derived Δ8,9-Pregnene (+)-03219A

From Metallacycle-Mediated Annulative Cross-Coupling to Steroidal Tetracycles through Intramolecular C9–C10 Bond Formation

Synthesis of Anhydroryanodol

Collaborators (3)

Christopher Coss

Matthew Hayes

Thomas P. Burris

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