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Grant Fischer

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Assistant Professor of Molecular Genetic Pathology (Tenure Track)

University of North Carolina at Chapel Hill

United States

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Recent Grants

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Integration of Epigenomics and Metabolomics into a Single Paradigm of Melanoma Virulence

Open Date: 2022-01-01

Close Date: 2025-07-01

Grant: Close

The Role of Oxidative Phosphorylation in the Pathogenesis of Melanoma Brain Metastases

Open Date: 2016-12-01

Close Date: 2018-06-01

Articles (14)

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2023

Collaborators (6)

Nandita Guha-Thakurta

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Greg M. Delgoffe

UNITED STATES

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Elizabeth Burton

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Aditya Mishra

University of Georgia

UNITED STATES

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Keith Ligon

Chief of Neuropathology/Principal Investigator

Dana-Farber Cancer Institute

UNITED STATES

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Ryan Chen

University of Massachusetts Chan Medical School

UNITED STATES

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Grant Fischer

Research Interests

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Recent Grants

Articles (14)

Genomic Profiling Reveals SMARCA4 Mutations Are Associated with Shorter Overall and Intracranial Progression-Free Survival in Patients with Melanoma Brain Metastases

Genomic profiling of pediatric mycosis fungoides, lymphomatoid papulosis z, and primary cutaneous anaplastic large cell lymphoma identifies recurrent tyrosine kinase gene fusions.

Preclinical models of melanoma leptomeningeal disease to assess intrathecal checkpoint blockade.

Loss of TET2 Facilitates Aggressive Behavior in Cutaneous Melanoma by Inducing PGC1α/Oxidative Phosphorylation (OXPHOS).

Undifferentiated Melanoma: A Clinicopathologic and Gene Expression Analysis Study With Identification of HMGA2 as a Diagnostic Marker.

Integrated analysis of molecular and clinical features associated with overall survival in melanoma patients with brain metastasis.

PRAME Expression in Melanoma is Negatively Regulated by TET2-Mediated DNA Hydroxymethylation.

Pembrolizumab-induced Stevens-Johnson Syndrome-Like Reaction: An Atypical Clinical Presentation

High-grade sarcoma arising within a cellular dermatofibroma.

A Comparative Genomic Study of Conventional and Undifferentiated Melanoma.

Concurrent intrathecal and intravenous nivolumab in leptomeningeal disease

Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma

Gene fusions in superficial mesenchymal neoplasms: Emerging entities and useful diagnostic adjuncts.

Anaplastic Kaposi Sarcoma: A Clinicopathologic and Molecular Genetic Analysis.

Collaborators (6)

Nandita Guha-Thakurta

Greg M. Delgoffe

Elizabeth Burton

Aditya Mishra

Keith Ligon

Ryan Chen

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