Grant O'Connell

Assistant Professor

Case Western Reserve University

United States

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Grant O'Connell is an Assistant Professor at Case Western Reserve University in the United States. His research focuses on neurological damage biomarkers, stroke identification, and transcriptomic studies involving blood samples. Recent publications highlight the importance of donor leukocyte counts in gene expression analysis and the diagnostic potential of blood biomarkers in conditions such as Alzheimer's disease and traumatic brain injury.

Articles (10)

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2024

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2024

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2023

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2023

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2022

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2021

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2021

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2020

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2020

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2020

Collaborators (2)

Megan Wenzell

Tenure-Track Assistant Professor

Case Western Reserve University

UNITED STATES

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Taura Barr

Ohio State University

UNITED STATES

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Grant O'Connell

Research Interests

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Articles (10)

Brain Expression Levels of Commonly Measured Blood Biomarkers of Neurological Damage Differ with Respect to Sex, Race, and Age

Dataset including whole blood gene expression profiles and matched leukocyte counts with utility for benchmarking cellular deconvolution pipelines

Donor white blood cell differential is the single largest determinant of whole blood gene expression patterns

Variability in donor leukocyte counts confound the use of common RNA sequencing data normalization strategies in transcriptomic biomarker studies performed with whole blood

Use of deep artificial neural networks to identify stroke during triage via subtle changes in circulating cell counts

Diagnostic accuracy of blood biomarkers for Alzheimer's disease and amnestic mild cognitive impairment: A meta-analysis

Newly-identified blood biomarkers of neurological damage are correlated with infarct volume in patients with acute ischemic stroke

Large-scale informatic analysis to algorithmically identify blood biomarkers of neurological damage

Use of high-sensitivity digital ELISA improves the diagnostic performance of circulating brain-specific proteins for detection of traumatic brain injury during triage

Bioinformatic analysis of brain-specific miRNAs for identification of candidate traumatic brain injury blood biomarkers

Collaborators (2)

Megan Wenzell

Taura Barr

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