Gregory Howard

Research Assistant Professor

Vanderbilt University

United States

Research Interests

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About

Dr. Gregory Howard is a Research Assistant Professor at Vanderbilt University in the United States. His research focuses on the treatment of hematologic malignancies and the molecular responses of cancer cells, particularly involving the p53–MDM4 axis and WDR5 WIN site inhibition. He has contributed significantly to the understanding of WD repeat domain 5 inhibitors and their therapeutic implications.

Articles (4)

Year:

2025

Year:

2024

Year:

2024

Year:

2024

Collaborators (2)

Christian Meyer

Assistant Member

St. Jude Children's Research Hospital

UNITED STATES

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William P Tansey

Vanderbilt University School of Medicine

UNITED STATES

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Gregory Howard

Research Interests

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Articles (4)

Ribosome-directed cancer therapies: the tip of the iceberg?

Expanded profiling of WD repeat domain 5 inhibitors reveals actionable strategies for the treatment of hematologic malignancies

Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

Collaborators (2)

Christian Meyer

William P Tansey

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