Grzegorz Litwinienko

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full professor, Principal Investigator

University of Warsaw

Poland

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Grzegorz Litwinienko is a Full Professor and Principal Investigator at the University of Warsaw, Poland. His research areas encompass nanotechnology applications in radiobiology, antioxidant mechanisms, and the evaluation of anticancer therapies. Recent articles reflect his focus on metallofullerenols, magnetic nanoplatforms for targeted therapy, and the development of novel therapeutic strategies against cancer.

Recent Grants

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Ugly, Dirty and Bad? - the quest for the mechanisms of antioxidant action of some nitrogen and sulfur compounds

Open Date: 2022-10-01

Close Date: 2026-10-01

Grant: Close

Electrospun nanofiber-based nanoplatform for delivery of new nutraceutical derivatives to eliminate chemotherapy-induced senescent breast cancer cells

Open Date: 2022-07-01

Close Date: 2026-07-01

Grant: Close

Nanomaterials with antioxidant activity: from design and mechanistic studies to potential applications

Open Date: 2022-02-01

Close Date: 2023-12-01

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Physico-chemical principles of antioxidant action: from solvent effect and mechanistic studies to interfacial phenomena in biologically relevant systems

Open Date: 2019-10-01

Close Date: 2023-09-01

Grant: Close

Physicochemical basis of the participation of nanoparticles in radical reactions – studies on the kinetics and mechanisms of the processes carried out in model lipid systems

Open Date: 2015-08-01

Close Date: 2018-09-01

Grzegorz Litwinienko

Research Interests

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About

Recent Grants

Articles (19)

Metallofullerenol Gd@C82(OH)22 preserves human erythrocyte plasma membrane integrity from AAPH-induced oxidative stress: Molecular mechanisms and antioxidant activity

Nanotechnology meets radiobiology: Fullerenols and Metallofullerenols as nano-shields in radiotherapy

Evaluation of anticancer activity of urotropine surface modified iron oxide nanoparticles using a panel of forty breast cancer cell lines

Design of a Magnetic Nanoplatform Based on CD26 Targeting and HSP90 Inhibition for Apoptosis and Ferroptosis-Mediated Elimination of Senescent Cells

Enhancing the Green Synthesis of Glycerol Carbonate: Carboxylation of Glycerol with CO2 Catalyzed by Metal Nanoparticles Encapsulated in Cerium Metal–Organic Frameworks

Antioxidant Activity of Bilirubin in Micellar and Liposomal Systems Is pH-Dependent

Kinetics of Metallofullerenol Reactions with the Products of Water Radiolysis: Implications for Radiotherapeutics

New Mitochondria-Targeted Fisetin Derivative Compromises Mitophagy and Limits Survival of Drug-Induced Senescent Breast Cancer Cells

Mutation Status and Glucose Availability Affect the Response to Mitochondria-Targeted Quercetin Derivative in Breast Cancer Cells

Fullerenol C<sub>60</sub>(OH)<sub>36</sub> Protects the Antioxidant Enzymes in Human Erythrocytes against Oxidative Damage Induced by High-Energy Electrons

Metallofullerenols in biomedical applications.

Mutual Activation of Two Radical Trapping Agents: Unusual “Win–Win Synergy” of Resveratrol and TEMPO during Scavenging of dpph• Radical in Methanol

Concentration-dependent HAT/ET mechanism of the reaction of phenols with 2,2-diphenyl-1-picrylhydrazyl (dpph˙) in methanol

Antiradical Activity of Dopamine, L-DOPA, Adrenaline, and Noradrenaline in Water/Methanol and in Liposomal Systems

Senolysis-Based Elimination of Chemotherapy-Induced Senescent Breast Cancer Cells by Quercetin Derivative with Blocked Hydroxy Groups

The Effect of Fullerenol C<sub>60</sub>(OH)<sub>36</sub> on the Antioxidant Defense System in Erythrocytes

Antioxidant activity of two edible isothiocyanates: Sulforaphane and erucin is due to their thermal decomposition to sulfenic acids and methylsulfinyl radicals

Unexpected Role of pH and Microenvironment on the Antioxidant and Synergistic Activity of Resveratrol in Model Micellar and Liposomal Systems

Hydrogen Atom Transfer from HOO• to ortho‐Quinones Explains the Antioxidant Activity of Polydopamine

Collaborators (17)

Adrian Konopko

Michal Wojcik

Monika Kluzek

Gabriela Betlej

Agnieszka Ciuraszkiewicz

Agnieszka Krogul-Sobczak

Jacek Grebowski

ELENA OBRADOR

Marian Wolszczak

Maciej Wnuk

Natalia Cichon

Luca Valgimigli

Pablo Martínez-Vicente

Anna Deręgowska

Katarzyna Jodko-Piórecka

Krzysztof Górny

Tomasz Szmatoła

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