Guangchun Bai

Assistant Professor

Albany Medical College

United States

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Dr. Guangchun Bai is an Assistant Professor at Albany Medical College in the United States. His research focuses on bacterial immunity and pathogenesis, particularly relating to Streptococcus pneumoniae and Mycobacterium species. Recent publications highlight his work on cyclic di-AMP as a second messenger involved in bacterial membrane integrity and immune response. Dr. Bai's studies contribute to understanding vaccine development and bacterial virulence mechanisms.

Articles (12)

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2025

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2025

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2024

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2023

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2023

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2022

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2022

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2022

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2021

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2020

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2020

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2020

Collaborators (5)

Matthew Jones

Boston University

UNITED STATES

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Elsa N. Bou Ghanem

University at Buffalo

UNITED STATES

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Richard M. Johnson

UNITED STATES

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Tiffany Zarrella

Assistant Professor

Georgetown University

UNITED STATES

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Lee J. Quinton

Boston University School of Medicine

UNITED STATES

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Guangchun Bai

Research Interests

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Articles (12)

Cyclic Di-AMP Affects Cell Membrane Integrity of Streptococcus pneumoniae.

Mucosal immunity elicited by a human-Fcγ receptor-I targeted intranasal vaccine platform enhances resistance against nasopharyngeal colonization of Streptococcus pneumoniae and induces broadly protective immunity against respiratory pathogens.

A bacterial vesicle-based pneumococcal vaccine against influenza-mediated secondary Streptococcus pneumoniae pulmonary infection.

Mycobacterial phosphodiesterase Rv0805 is a virulence determinant and its cyclic nucleotide hydrolytic activity is required for propionate detoxification

Bacterial second messenger cyclic di-AMP in streptococci.

Editorial: Transmission, colonization, and molecular pathogenesis of pneumococcus.

Cyclic-di-AMP Phosphodiesterase Elicits Protective Immune Responses Against <i>Mycobacterium tuberculosis</i> H37Ra Infection in Mice.

c-di-AMP Accumulation Regulates Growth, Metabolism, and Immunogenicity of <i>Mycobacterium smegmatis</i>.

New Mechanistic Insights into Purine Biosynthesis with Second Messenger c-di-AMP in Relation to Biofilm-Related Persistent Methicillin-Resistant Staphylococcus aureus Infections

The Many Roles of the Bacterial Second Messenger Cyclic di-AMP in Adapting to Stress Cues

Unique Roles for <i>Streptococcus pneumoniae</i> Phosphodiesterase 2 in Cyclic di-AMP Catabolism and Macrophage Responses.

Bacterial Second Messenger Cyclic di-AMP Modulates the Competence State in Streptococcus pneumoniae.

Collaborators (5)

Matthew Jones

Elsa N. Bou Ghanem

Richard M. Johnson

Tiffany Zarrella

Lee J. Quinton

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