Guy M. Lenk

University of Michigan

United States

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Articles (5)

Year:

2024

Year:

2023

Year:

2022

Year:

2021

Year:

2020

Collaborators (3)

Miriam H Meisler

University of Michigan

UNITED STATES

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Ernest Turro

Icahn School of Medicine at Mount Sinai

UNITED STATES

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Julie Ziobro

Clinical Assistant Professor

University of Michigan

UNITED STATES

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Guy M. Lenk

Research Interests

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Articles (5)

Biallelic loss-of-function variants of SLC12A9 cause lysosome dysfunction and a syndromic neurodevelopmental disorder.

Altered phenotypes due to genetic interaction between the mouse phosphoinositide biosynthesis genes Fig4 and Pip4k2c.

Chloroquine corrects enlarged lysosomes in FIG4 null cells and reduces neurodegeneration in Fig4 null mice.

AAV9-mediated FIG4 delivery prolongs life span in Charcot-Marie-Tooth disease type 4J mouse model

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome

Collaborators (3)

Miriam H Meisler

Ernest Turro

Julie Ziobro

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