Guy Salvesen

Professor

Sanford Burnham Prebys Medical Discovery Institute

United States

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Guy Salvesen is a Professor at the Sanford-Burnham Medical Research Institute in the United States. His research focuses on proteolytic enzymes and their role in various diseases, including multiple myeloma and Von Hippel–Lindau syndrome. Recent publications include studies on metalloproteinases, caspases, and the mechanisms of NETosis and pyroptosis.

Articles (6)

Year:

2022

Year:

2021

Year:

2020

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2020

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2020

Year:

2020

Collaborators (1)

Paulina Kasperkiewicz

Adjunct Professor

Wroclaw University of Science and Technology

POLAND

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Guy Salvesen

Research Interests

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Articles (6)

Gain of function of a metalloproteinase associated with multiple myeloma, bicuspid aortic valve, and Von Hippel–Lindau syndrome

Engineering caspase 7 as an affinity reagent to capture proteolytic products

NETosis occurs independently of neutrophil serine proteases

Multiplexed Probing of Proteolytic Enzymes Using Mass Cytometry-Compatible Activity-Based Probes

Extended subsite profiling of the pyroptosis effector protein gasdermin D reveals a region recognized by inflammatory caspase-11

Selective inhibition of matrix metalloproteinase 10 (MMP10) with a single-domain antibody

Collaborators (1)

Paulina Kasperkiewicz

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