Hakon Leffler

Associate Professor - Professor

Lund University

Sweden

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Articles (10)

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Collaborators (12)

Helen Blanchard

Established Professor of Chemistry

University of Galway

IRELAND

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Demetres Leonidas

Professor

University of Thessaly

GREECE

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Robert Slack

VP and Head of Pharmacology

UNITED KINGDOM

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Yoshiki Narimatsu

Københavns Universitet

DENMARK

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Kristian Stengaard-Pedersen

Aarhus University

DENMARK

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Bent Deleuran

Aarhus University

DENMARK

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Marko Anderluh

SLOVENIA

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Anne Imberty

Université Grenoble Alpes

FRANCE

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Daniel Ricklin

Associate Professor

University of Basel

SWITZERLAND

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Tue Wenzel Kragstrup

Aarhus University

DENMARK

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Ola Blixt

Københavns Universitet

DENMARK

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Tihomir Tomašič

SLOVENIA

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Hakon Leffler

Research Interests

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Articles (10)

Strong Binding of C-Glycosylic1,2-Thiodisaccharides to Galectin-3─Enthalpy-Driven Affinity Enhancement by Water-Mediated Hydrogen Bonds

Increased Galectin-9 Levels Correlate with Disease Activity in Patients with DMARD-Naïve Rheumatoid Arthritis and Modulate the Secretion of MCP-1 and IL-6 from Synovial Fibroblasts

Front Cover: Selective Monovalent Galectin‐8 Ligands Based on 3‐Lactoylgalactoside (ChemMedChem 3/2022)

Selective Monovalent Galectin‐8 Ligands Based on 3‐Lactoylgalactoside

Installation of O-glycan sulfation capacities in human HEK293 cells for display of sulfated mucins

Engineering the Ligand Specificity of the Human Galectin‐1 by Incorporation of Tryptophan Analogues

Discovery and Optimization of the First Highly Effective and Orally Available Galectin-3 Inhibitors for Treatment of Fibrotic Disease

Galectin-9 Signaling Drives Breast Cancer Invasion through Extracellular Matrix

Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia

Chemokines modulate glycan binding and the immunoregulatory activity of galectins

Collaborators (12)

Helen Blanchard

Demetres Leonidas

Robert Slack

Yoshiki Narimatsu

Kristian Stengaard-Pedersen

Bent Deleuran

Marko Anderluh

Anne Imberty

Daniel Ricklin

Tue Wenzel Kragstrup

Ola Blixt

Tihomir Tomašič

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