Hans-Martin Jäck

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Director and Professor of Immunology

University of Erlangen-Nuremberg

Germany

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About

Hans-Martin Jäck is the Director and Professor of Immunology at the University of Erlangen-Nuremberg in Germany. His research primarily focuses on B cell maturation, SARS-CoV-2 lineages, and innovative methods for genetic manipulation in mammalian cells. Recent articles have explored topics such as antibody-mediated neutralization and the virological traits of emerging SARS-CoV-2 variants.

Recent Grants

Grant: Close

B cells and beyond (MGK)

Open Date: 2013-01-01

Close Date:

Grant: Close

microRNA-controlled generation and maintenance of humoral memory (09)

Open Date: 2013-01-01

Close Date:

Grant: Close

GRK 1660: Key Signals of Adaptive Immune Response

Open Date: 2010-01-01

Close Date:

Grant: Close

Autumn School Current Concepts in Immunology

Open Date: 2009-01-01

Close Date: 2011-12-31

Grant: Close

Function of the cripple-like factor 2 (KLF2) in the B-cell homeostasis and humoral immune response

Open Date: 2007-01-01

Close Date: 2014-12-31

Articles (13)

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2025

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2025

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2024

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2024

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2023

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2023

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2023

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2022

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2022

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2021

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2021

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2021

Collaborators (7)

Jürgen Wittmann

Friedrich-Alexander Universität Erlangen-Nürnberg

GERMANY

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Amélie Bonaud

INSERM

FRANCE

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Jutta Eichler

Professor

Friedrich-Alexander Universität Erlangen-Nürnberg

GERMANY

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Stefan Pöhlmann

Head of Infection Biology Unit

German Primate Center

GERMANY

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Marion Espéli

FRANCE

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Antonia Sophia Peter

GERMANY

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Patrick Morhart

Friedrich-Alexander Universität Erlangen-Nürnberg

GERMANY

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Hans-Martin Jäck

Research Interests

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Recent Grants

Articles (13)

B cell maturation antigen (BCMA) is dispensable for the survival of long-lived plasma cells

Entry Efficiency, Protease Dependence, and Antibody-Mediated Neutralization of SARS-CoV-2 Sublineages KP.3.1.1 and XEC

An Enhanced Retroviral Vector for Efficient Genetic Manipulation and Selection in Mammalian Cells

Virological Traits of the SARS-CoV-2 BA.2.87.1 Lineage

Comparative Analysis of Host Cell Entry Efficiency and Neutralization Sensitivity of Emerging SARS-CoV-2 Lineages KP.2, KP.2.3, KP.3, and LB.1

Identification of miR-128 Target mRNAs That Are Expressed in B Cells Using a Modified Dual Luciferase Vector

Host cell entry and neutralisation sensitivity of the SARS-CoV-2 XBB.1.16 lineage

Profound neutralization evasion and augmented host cell entry are hallmarks of the fast-spreading SARS-CoV-2 lineage XBB.1.5

A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS‐CoV‐2 infection model

Efficient antibody evasion but reduced ACE2 binding by the emerging SARS-CoV-2 variant B.1.640.2

Single-cell resolution of plasma cell fate programming in health and disease.

TFG is required for autophagy flux and to prevent endoplasmic reticulum stress in CH12 B lymphoma cells

A surrogate cell-based SARS-CoV-2 spike blocking assay

Collaborators (7)

Jürgen Wittmann

Amélie Bonaud

Jutta Eichler

Stefan Pöhlmann

Marion Espéli

Antonia Sophia Peter

Patrick Morhart

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