Hans Zempel

Germany

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Articles (11)

Year:

2023

Year:

2023

Year:

2022

Year:

2022

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2022

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2022

Year:

2021

Year:

2021

Year:

2021

Year:

2021

Year:

2021

Collaborators (4)

Michael Bell-Simons

University Hospital

GERMANY

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Christoph Köhler

GERMANY

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Marc Spehr

Full Professor

RWTH Aachen University

GERMANY

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Geraldine Zimmer-Bensch

Professor

RWTH Aachen University

GERMANY

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Hans Zempel

Research Interests

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Contact this professor

Articles (11)

Suppression of mature TAU isoforms prevents Alzheimer's disease-like amyloid-beta oligomer-induced spine loss in rodent neurons

Microtubule affinity regulating kinase (MARK/Par1) isoforms differentially regulate Alzheimer-like TAU missorting and Aβ-mediated synapse pathology

AAV-based gene therapy approaches for genetic forms of tauopathies and related neurogenetic disorders

A mitochondria cluster at the proximal axon initial segment controls axodendritic TAU trafficking in rodent primary and human iPSC-derived neurons

A simple human cell model for TAU trafficking and tauopathy-related TAU pathology

SH-SY5Y-derived neurons: A human neuronal model system for investigating TAU sorting and neuronal subtype-specific TAU vulnerability

DNA Methyltransferase 1 (DNMT1) Shapes Neuronal Activity of Human iPSC-Derived Glutamatergic Cortical Neurons.

DNA Methylation in Genetic and Sporadic Forms of Neurodegeneration: Lessons from Alzheimer’s, Related Tauopathies and Genetic Tauopathies

A perspective on human cell models for POLG-spectrum disorders: Advantages and disadvantages of CRISPR-Cas-based vs. patient-derived iPSC models

Axonal TAU Sorting Requires the C-terminus of TAU but is Independent of ANKG and TRIM46 Enrichment at the AIS

Differential Effects of the Six Human TAU Isoforms: Somatic Retention of 2N-TAU and Increased Microtubule Number Induced by 4R-TAU

Collaborators (4)

Michael Bell-Simons

Christoph Köhler

Marc Spehr

Geraldine Zimmer-Bensch

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