Haribabu Arthanari

Associate Professor

Dana-Farber Cancer Institute

United States

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Haribabu Arthanari is an Associate Professor at Dana-Farber Cancer Institute in the United States. His research focuses on the structural and functional aspects of proteins related to diseases such as cancer and neurodegeneration. Recent publications include studies on SARS-CoV-2 inhibitors, TORC1 regulation in response to amino acid availability, and the mechanics of α-synuclein dysfunction in Parkinson's disease.

Articles (10)

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2022

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2021

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2021

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2021

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2021

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2021

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2021

Collaborators (7)

Thibault Viennet

Assistant Professor

Aarhus University

DENMARK

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Thanos Halazonetis

Professor

University of Geneva

SWITZERLAND

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Manuel Etzkorn

GERMANY

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Gerhard Wagner

Professor

Harvard Medical School

UNITED STATES

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David Joseph

Max-Planck-Institut für biophysikalische Chemie

GERMANY

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Dennis J. Selkoe

Vincent and Stella Coates Professor of Neurologic Diseases

Harvard Medical School

UNITED STATES

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Jingyu Zhang

University of Pittsburgh

UNITED STATES

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Haribabu Arthanari

Research Interests

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Articles (10)

Non-covalent SARS-CoV-2 M<sup>pro</sup> inhibitors developed from in silico screen hits.

VirtualFlow Ants—Ultra-Large Virtual Screenings with Artificial Intelligence Driven Docking Algorithm Based on Ant Colony Optimization

Altered conformation of α-synuclein drives dysfunction of synaptic vesicles in a synaptosomal model of Parkinson’s disease

The structural basis of PTEN regulation by multi-site phosphorylation.

Local deuteration enables NMR observation of methyl groups in proteins from eukaryotic and cell-free expression systems.

The fission yeast FLCN/FNIP complex augments TORC1 repression or activation in response to amino acid (AA) availability.

A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders.

Hanudatta S. Atreya (1974-2020).

Allosterically Coupled Multisite Binding of Testosterone to Human Serum Albumin.

Optimization of phase dispersion enables broadband excitation without homonuclear coupling artifacts.

Collaborators (7)

Thibault Viennet

Thanos Halazonetis

Manuel Etzkorn

Gerhard Wagner

David Joseph

Dennis J. Selkoe

Jingyu Zhang

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