Harikrishna Nakshatri

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Professor

Indiana State University

United States

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About

Dr. Harikrishna Nakshatri is a Professor at Indiana University, USA. His research focuses on breast cancer, specifically in areas such as integrative data analysis for target discovery, spatial glycomics, signaling pathways influenced by oxygen tension, and the characterization of biomarkers for cancer initiation. Recent publications highlight his work on the impacts of targeted therapies, the cancer cell kinome, and preclinical modeling to enhance clinical translation in oncology.

Recent Grants

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Mechanisms targeting triple negative breast cancer genomic vulnerability

Open Date: 2018-12-01

Close Date: 2021-11-01

Grant: Close

The effect of extra physiologic oxygen shock/stress on cancer stem cell and drug sensitivity measurements

Open Date: 2018-11-01

Close Date: 2020-11-01

Grant: Close

Taxonomy of the normal breast-a pilot study

Open Date: 2018-09-01

Close Date: 2020-08-01

Grant: Close

Impact of NF-kB methylation on chemoresistance and metastasis of breast cancer

Open Date: 2018-01-01

Close Date: 2019-12-01

Grant: Close

The impact of ethnicity-dependent differences in breast epithelial cell hierarchy on tumor incidence and characteristics

Open Date: 2015-09-01

Close Date: 2019-08-01

Articles (15)

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2025

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2024

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2024

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2024

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2021

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2021

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2021

Collaborators (15)

Christiane Löhr

Professor

Oregon State University

UNITED STATES

Harikrishna Nakshatri

Research Interests

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About

Recent Grants

Articles (15)

MammOnc-DB, an integrative breast cancer data analysis platform for target discovery

Spatial N-glycomics of the normal breast microenvironment reveals fucosylated and high-mannose N-glycan signatures related to BI-RADS density and ancestry

Oxygen tension-dependent variability in the cancer cell kinome impacts signaling pathways and response to targeted therapies

Mutant RAS-driven Secretome Causes Skeletal Muscle Defects in Breast Cancer

Identification and Characterization of a Small Molecule Bcl-2 Functional Converter

Effects of Gemcitabine/Nab-Paclitaxel and DMAPT in PDAC Cachexia in vivo and in vitro

Evaluating the Effects of Targeted Drug Therapies for 8q24.3 Amplified Breast Cancer

Modeling Preclinical Cancer Studies under Physioxia to Enhance Clinical Translation

Acquisition, processing, and single-cell analysis of normal human breast tissues from a biobank

FAM83A is a potential biomarker for breast cancer initiation.

Aberrant epigenetic and transcriptional events associated with breast cancer risk.

Tumor collection/processing under physioxia uncovers highly relevant signaling networks and drug sensitivity.

Bidirectional Regulatory Cross-Talk between Cell Context and Genomic Aberrations Shapes Breast Tumorigenesis

Aged Breast Extracellular Matrix Drives Mammary Epithelial Cells to an Invasive and Cancer‐Like Phenotype

Antitumor properties of novel sesquiterpene lactone analogs as NFκB inhibitors that bind to the IKKβ ubiquitin-like domain (ULD)

Collaborators (15)

Christiane Löhr

Brittany Counts

Gokhan Bahcecioglu

Emma Doud

Siyuan Zhang

Teresa A. Zimmers

Austyn Colter

Yeonhee Park

Zhaohui Qin

SHA CAO

Erin Howe

Yunlong Liu

Ruizhong Wang

Natascia Marino

Richard Drake

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