Hassane Mchaourab

Professor

Vanderbilt University

United States

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Professor Hassane Mchaourab is a faculty member at Vanderbilt University, USA. His research primarily focuses on protein conformational dynamics, particularly utilizing advanced techniques such as AlphaFold2 and Double Electron Electron Resonance (DEER). Recent articles authored by Professor Mchaourab explore topics including the molecular architecture of protein complexes and the mechanisms of ATP-coupled transport processes.

Articles (9)

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2025

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2024

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2023

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2022

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2022

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2022

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2022

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University of Virginia School of Medicine

UNITED STATES

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Hassane Mchaourab

Research Interests

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Articles (9)

Modeling protein conformational ensembles by guiding AlphaFold2 with Double Electron Electron Resonance (DEER) distance distributions

Conformational cycle of a protease-containing ABC transporter in lipid nanodiscs reveals the mechanism of cargo-protein coupling

Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter

Molecular architecture of the human caveolin-1 complex

Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter

SPEACH_AF: Sampling protein ensembles and conformational heterogeneity with Alphafold2

Sampling alternative conformational states of transporters and receptors with AlphaFold2

Protein functional dynamics from the rigorous global analysis of DEER data: Conditions, components, and conformations

Methodology for rigorous modeling of protein conformational changes by Rosetta using DEER distance restraints

Collaborators (5)

Benjamin Brown

Tarjani Thaker

Mahmoud Moradi

Thomas Tomasiak

Anne Kenworthy

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