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Heather Melichar

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Associate Professor

McGill University

Canada

Research Interests

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Professors in Canada Professors in Immunology Immunology professors in Canada

Recent Grants

Grant: Open

“Tracking the fate of self-reactive T cells after checkpoint blockade

Open Date: 2026-09-01

Close Date: 2028-08-01

Grant: Open

De- (and Re-) constructing T cell development through T cell receptor signals

Open Date: 2026-04-01

Close Date: 2031-03-01

Grant: Open

The mechano-regulation of naive T cell survival: consequences for aging and autoimmunity.

Open Date: 2025-10-01

Close Date: 2030-09-30

Grant: Close

Montreal Immunology Meetings Annual Symposium: Modulation of the immune system by environmental factors

Open Date: 2024-11-01

Close Date: 2025-10-31

Grant: Open

Tuning-up thymopoiesis by targeting interleukin-21 to the bone marrow

Open Date: 2024-10-01

Close Date: 2029-09-30

Articles (16)

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McGill University

CANADA

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Sergio Crespo-Garcia

Assistant Professor

Université de Montréal

CANADA

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De'Broski Herbert

Professor

University of Pennsylvania

UNITED STATES

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Momoko Yoshimoto

Professor

Western Michigan University Homer Stryker MD School of Medicine

UNITED STATES

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Sébastien This

McGill University

CANADA

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Jean-Sébastien Joyal

Professor

Université de Montréal

CANADA

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Frédérick A. Mallette

Researcher / Investigator

Université de Montréal

CANADA

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Université de Montréal

CANADA

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Johannes Textor

Radboud University Medical Center

NETHERLANDS

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Heather Melichar

Research Interests

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Recent Grants

Articles (16)

Calibrating T cell responsiveness through interactions with self.

GFI1 as a novel regulator of γδ T cell development and the IL-17/IFN-γ lineage commitment.

Interleukin-17-Producing γδ T Cells Originate from SOX13&lt;sup&gt;+&lt;/sup&gt; Progenitors that Are Independent of γδTCR Signaling.

A type 1 immune-stromal cell network mediates disease tolerance against intestinal infection.

Unbiased analysis of NUP98-KDM5A-induced murine leukemia reveals phenotypic heterogeneity recapitulating human disease subtypes.

A Retrospective Analysis of Leadership, Awardees, and Member Gender Representation of the Canadian Society for Immunology

Machine learning predictions of T cell antigen specificity from intracellular calcium dynamics

Skewed epithelial cell differentiation and premature aging of the thymus in the absence of vitamin D signaling.

Type I interferon induced during chronic viral infection favors B-cell development in the thymus.

Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation

Early-life peripheral infections reprogram retinal microglia and aggravate neovascular age-related macular degeneration in later life

Cutting Edge: Aire Is a Coactivator of the Vitamin D Receptor

Machine learning analysis of the T cell receptor repertoire identifies sequence features of self-reactivity

CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax

Equity, Diversity and Inclusion in Canadian immunology: communication and complexity.

Revealing the identity of regulatory T-cell-suppressed self-reactive CD4&lt;sup&gt;+&lt;/sup&gt; T cells.

Collaborators (21)

Martin J. Richer

Santiago Costantino

François Mercier

S M Mansour Haeryfar

Ludger Klein

Stephanie Condotta

Byron Au-Yeung

John H. White

Sergio Crespo-Garcia

De'Broski Herbert

Momoko Yoshimoto

Sébastien This

Jean-Sébastien Joyal

Frédérick A. Mallette

Guillaume Blot

Judith Mandl

Aaron Marshall

Kathrin Kalies

Elliot Drobetsky

Przemyslaw Sapieha

Johannes Textor

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Interleukin-17-Producing γδ T Cells Originate from SOX13<sup>+</sup> Progenitors that Are Independent of γδTCR Signaling.

Revealing the identity of regulatory T-cell-suppressed self-reactive CD4<sup>+</sup> T cells.