Heather O'Hagan

Associate Professor

Indiana University School of Medicine

United States

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Articles (12)

Year:

2024

Year:

2022

Year:

2022

Year:

2022

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2022

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2022

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2021

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2021

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2021

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2021

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2021

Year:

2021

Collaborators (4)

Emma Doud

Assistant Research Professor

Indiana University School of Medicine

UNITED STATES

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THOMAS HURLEY

Professor

Indiana State University

UNITED STATES

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Katelyn Tepper

University of Indianapolis

UNITED STATES

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Gabriel E Zentner

Indiana State University

UNITED STATES

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Heather O'Hagan

Research Interests

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Articles (12)

Single-Cell Profiling Reveals the Impact of Genetic Alterations on the Differentiation of Inflammation-Induced Murine Colon Tumors

Bis-aryl-α,β-unsaturated ketone (ABK) chaperonin inhibitors exhibit selective cytotoxicity to colorectal cancer cells that correlates with levels of aberrant HSP60 in the cytosol.

Single-cell analysis of a high-grade serous ovarian cancer cell line reveals transcriptomic changes and cell subpopulations sensitive to epigenetic combination treatment.

A Novel ALDH1A1 Inhibitor Blocks Platinum-Induced Senescence and Stemness in Ovarian Cancer

Platinum-induced mitochondrial OXPHOS contributes to cancer stem cell enrichment in ovarian cancer.

Colon Tumors in Enterotoxigenic Bacteroides fragilis (ETBF)-Colonized Mice Do Not Display a Unique Mutational Signature but Instead Possess Host-Dependent Alterations in the APC Gene.

LSD1 and Aberrant DNA Methylation Mediate Persistence of Enteroendocrine Progenitors That Support <i>BRAF</i>-Mutant Colorectal Cancer.

Exploiting the HSP60/10 chaperonin system as a chemotherapeutic target for colorectal cancer.

Bacterial-Driven Inflammation and Mutant <i>BRAF</i> Expression Combine to Promote Murine Colon Tumorigenesis That Is Sensitive to Immune Checkpoint Therapy.

How Epigenetic Therapy Beats Adverse Genetics in Monosomy Karyotype AML.

Consensus molecular subtyping of colorectal cancers is influenced by goblet cell content.

LSD1 and Aberrant DNA Methylation Mediate Persistence of Enteroendocrine Progenitors That Support BRAF-Mutant Colorectal Cancer

Collaborators (4)

Emma Doud

THOMAS HURLEY

Katelyn Tepper

Gabriel E Zentner

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