Helena Felgueiras

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University of Minho
Country flagPortugal

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Recent Grants

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Electrospun nanofiber films modified with WAAPV peptide inhibit bacterial and proteolytic enzyme action in diabetic foot ulcers

Open Date: 2023-10-01

Close Date:

Grant: Close

CW49 peptide as a potential antimicrobial agent against the most prevalent bacteria colonizing diabetic foot ulcers

Open Date: 2022-10-01

Close Date: 2023-09-30

Grant: Close

Bilayer spun scaffolds modified with Tiger 17 and essential oils as active, target-directed platforms for the treatment of diabetic ulcers

Open Date: 2022-10-01

Close Date:

Grant: Close

MicroCoolPav: Coaxial Microfibers incorporated with Phase Change Materials for Cool Pavements

Open Date: 2022-01-01

Close Date:

Grant: Close

STarLig: Bacterial cell-specific targeting and nanoparticle-mediated bactericidal action against the most common pathogens colonizing diabetic foot ulcers

Open Date: 2022-01-01

Close Date: 2023-03-30

Articles (10)

The potential of nanoparticles as effective drug delivery systems combined with the versatility of fibers has led to the development of new and improved strategies to help in the diagnosis and treatment of diseases. Nanoparticles have extraordinary characteristics that are helpful in several applications, including wound dressings, microbial balance approaches, tissue regeneration, and cancer treatment. Owing to their large surface area, tailor-ability, and persistent diameter, fibers are also used for wound dressings, tissue engineering, controlled drug delivery, and protective clothing. The combination of nanoparticles with fibers has the power to generate delivery systems that have enhanced performance over the individual architectures. This review aims at illustrating the main possibilities and trends of fibers functionalized with nanoparticles, focusing on inorganic and organic nanoparticles and polymer-based fibers. Emphasis on the recent progress in the fabrication procedures of several types of nanoparticles and in the description of the most used polymers to produce fibers has been undertaken, along with the bioactivity of such alliances in several biomedical applications. To finish, future perspectives of nanoparticles incorporated within polymer-based fibers for clinical use are presented and discussed, thus showcasing relevant paths to follow for enhanced success in the field.

Year:

2023

The brown macroalgae of the species Rugulopteryx okamurae has reached European waters and the Strait of Gibraltar as an invasive species. The proliferation and colonization of the species in subtidal and intertidal zones of these regions imposes significant threats to local ecosystems and additionally represents a significant socioeconomic burden related to the large amounts of biomass accumulated as waste. As a way to minimize the effects caused by the accumulation of algae biomass, investigations have been made to employ this biomass as a raw material in value-added products or technologies. The present review explores the potential uses of R. okamurae, focusing on its impact for biogas production, composting, bioplastic and pharmaceutical purposes, with potential anti-inflammatory, antibacterial and α-glucosity inhibitory activities being highlighted. Overall, this species appears to present many attributes, with remarkable potential for uses in several fields of research and in various industries.

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2023

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

Collaborators (3)

Joana C. Antunes

University of Minho

PORTUGAL
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Maria Manuela Silva

University of Minho

PORTUGAL
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Sílvia Pereira-Lima

Professor Auxiliar

University of Minho

PORTUGAL
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