Hideaki Yano

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Northeastern University

United States

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Recent Grants

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NARSAD Young Investigator Award

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Articles (9)

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2023

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2023

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2022

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2021

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2021

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2020

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2020

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2020

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2020

Collaborators (5)

Alessandro Piergentili

University of Camerino

ITALY

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Alessandro Bonifazi

Associate Professor

University of Texas Medical Branch at Galveston

UNITED STATES

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Gianfabio Giorgioni

Assistant Professor

University of Camerino

ITALY

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Maria Giovanna Sabbieti

ITALY

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Kirill A. Martemyanov

University of Florida

UNITED STATES

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Hideaki Yano

Research Interests

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Recent Grants

Articles (9)

Fine-tuning GPCR-mediated neuromodulation by biasing signaling through different G protein subunits.

Subtle Structural Modification of a Synthetic Cannabinoid Receptor Agonist Drastically Increases its Efficacy at the CB1 Receptor

Highly Potent and Selective Dopamine D<sub>4</sub> Receptor Antagonists Potentially Useful for the Treatment of Glioblastoma.

Chirality of Novel Bitopic Agonists Determines Unique Pharmacology at the Dopamine D3 Receptor.

A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.

Positive Allosteric Modulation of the 5-HT1A Receptor by Indole-Based Synthetic Cannabinoids Abused by Humans.

A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity

Distinct inactive conformations of the dopamine D2 and D3 receptors correspond to different extents of inverse agonism.

The Glu102 mutation disrupts higher-order oligomerization of the sigma 1 receptor

Collaborators (5)

Alessandro Piergentili

Alessandro Bonifazi

Gianfabio Giorgioni

Maria Giovanna Sabbieti

Kirill A. Martemyanov

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