Hiroaki Niitsu

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Associate Professor (Special Appointment)

Hiroshima University Hospital

Japan

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About

Hiroaki Niitsu is an Associate Professor (Special Appointment) at Hiroshima University Hospital, Japan. His research focuses on oncology, particularly in the areas of urothelial carcinoma, prostate cancer, and colorectal cancer. His recent publications include studies on genomic profiling and the clinicopathological characteristics of various cancer types, contributing to improved understanding and treatment options in cancer care.

Recent Grants

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The impact of interactions between gut microbiota-derived hydrogen sulfide and GTP metabolism on intestinal epithelial cell function: dietary intervention as a regulatory strategy

Open Date: 2025-08-01

Close Date:

Grant: Open

The mechanism of GTP metabolic reprograming in colorectal cancer and the development of molecularly-targeted therapy by drug repositioning

Open Date: 2025-04-01

Close Date: 2028-03-01

Grant: Close

Tumor microenvironment of colorectal cancer in Lynch Syndrome

Open Date: 2024-07-01

Close Date: 2025-03-01

Grant: Close

Biological significance of EGFR expression in stroma of colorectal cancer and its impact on drug resistance to MAPK signal inhibitors

Open Date: 2023-04-01

Close Date: 2025-03-01

Grant: Close

Investigation of resistant mechanisms to novel KRAS inhibitors in mutant KRAS colorectal cancers by utilizing three-dimensional cell culture recapitulating tumor microenvironment

Open Date: 2022-10-01

Close Date: 2024-03-01

Articles (10)

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2025

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2024

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2023

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2022

Collaborators (2)

Keisuke Goto

Hiroshima University

JAPAN

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Avlant Nilsson

Assistant Professor at Karolinska Institutet

Karolinska Institutet

SWEDEN

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Hiroaki Niitsu

Research Interests

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Recent Grants

Articles (10)

Clinicopathological Characteristics of Upper Tract Urothelial Cancer With Loss of Immunohistochemical Expression of Mismatch Repair Proteins

TUBB3 Is Associated With a Poor Prognosis and Basal Subtypes in Upper and Lower Tract Urothelial Carcinoma.

Comprehensive Genomic Profiling Testing for Castration‐Resistant Prostate Cancer in Advanced Elderly Patients: A Single‐Center Retrospective Cohort Study

A Sister Mary Joseph’s nodule in fallopian tube cancer: exploring the metastatic pathway through gene expression profiling—a case report

Nectin-4 expression in upper and lower tract urothelial carcinoma: correlation with early-stage disease and prognostic relevance.

The usefulness of comprehensive genome profiling test in screening of Lynch syndrome independent of the conventional clinical screening or microsatellite instability tests

Real-world data analysis for factors influencing the quality check status in FoundationOne CDx cancer genomic profiling tests

Right-sided versus left-sided colorectal cancer in elderly patients: a sub-analysis of a large multicenter case-control study in Japan.

Development of Pluoronic nanoparticles of fluorocoxib A for endoscopic fluorescence imaging of colonic adenomas.

Cancer-Associated Fibroblasts and Squamous Epithelial Cells Constitute a Unique Microenvironment in a Mouse Model of Inflammation-Induced Colon Cancer

Collaborators (2)

Keisuke Goto

Avlant Nilsson

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