Hiroaki Taniguchi

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Associate Professor

Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences

Poland

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About

Dr. Hiroaki Taniguchi is an Associate Professor at the Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences. His research primarily focuses on genetic variations related to dairy production traits and innovative gene editing techniques, as highlighted in his recent publications. Additionally, he explores applications in precision medicine and the molecular mechanisms underlying neurodegenerative diseases and liver cancer.

Recent Grants

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BovReg-Identification of functionally active genomic features relevant to phenotypic diversity and plasticity in cattle

Open Date: 2019-09-01

Close Date: 2024-02-01

Grant: Close

Badanie wpływu przerwania sieci transkrypcyjnych na rozwój raka wątroby: analiza funkcjonalna mutacji genu HNF4A z wykorzystaniem systemu CRISPR/Cas9

Open Date: 2018-02-01

Close Date: 2023-01-01

Grant: Close

Mechanism of liver cancer development and malignant due to mutations of the nuclear receptor HNF4A

Open Date: 2015-04-01

Close Date: 2017-03-01

Grant: Close

Cancer progression caused by dysfunction of cellular metabolism and epigenetics

Open Date: 2013-04-01

Close Date: 2016-12-01

Grant: Close

Analysis of glutathione dynamics and neurodegenerative disease using a redox control transcription factor Nrf1 deficient mice

Open Date: 2013-04-01

Close Date: 2014-03-01

Articles (18)

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2025

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2021

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2021

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2021

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2021

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2020

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2020

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2020

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2020

Collaborators (7)

Brygida Ślaska

University of Life Sciences in Lublin

POLAND

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Chandra S Pareek

professor

Nicolaus Copernicus University

POLAND

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Leyland Fraser

Professor

University of Warmia and Mazury in Olsztyn

POLAND

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Hidesato Ogawa

JAPAN

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Kamila Patrycja Liput

Institute of Biochemistry and Biophysics, Polish Academy of Sciences

POLAND

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Piotr Poznański

Adjunct Professor

Institute of Genetics and Animal Breeding

POLAND

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Christopher Wardell

Assistant Professor

University of Arkansas for Medical Sciences

UNITED STATES

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Hiroaki Taniguchi

Research Interests

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About

Recent Grants

Articles (18)

Discovery of a regulatory polymorphism in the bovine PICALM gene associated with milk αS1‐casein concentration

A simple validation and screening method for CRISPR/Cas9-mediated gene editing in mouse embryos to facilitate genetically modified mice production

Identification of a functional single nucleotide polymorphism in the FASN promoter associated with milk fat traits in dairy cattle

A regionally based precision medicine implementation initiative in North Africa:The PerMediNA consortium

Establishment of a cloning-free CRISPR/Cas9 protocol to generate large deletions in the bovine MDBK cell line

Microproteomic-Based Analysis of the Goat Milk Protein Synthesis Network and Casein Production Evaluation.

NFE2L1/Nrf1 serves as a potential therapeutical target for neurodegenerative diseases.

Liver Cancer 2.0.

Oncogenic Mutation BRAF V600E Changes Phenotypic Behavior of THLE-2 Liver Cells through Alteration of Gene Expression

HNF1A POU Domain Mutations Found in Japanese Liver Cancer Patients Cause Downregulation of HNF4A Promoter Activity with Possible Disruption in Transcription Networks

Molecular Characterisation of Uterine Endometrial Proteins during Early Stages of Pregnancy in Pigs by MALDI TOF/TOF

Disruption of tumor suppressors hnf4α /hnf1α causes tumorigenesis in liver

Nrf2 dlg domain mutations identified in japanese liver cancer patients affect the transcriptional activity in hcc cell lines

Xanthohumol for human malignancies: Chemistry, pharmacokinetics and molecular targets

Deletion of the prdm3 gene causes a neuronal differentiation deficiency in p19 cells

Emerging Roles of PRDM Factors in Stem Cells and Neuronal System: Cofactor Dependent Regulation of PRDM3/16 and FOG1/2 (Novel PRDM Factors)

Emerging braf mutations in cancer progression and their possible effects on transcriptional networks

Epidemiology, clinical features, and impact of food habits on the risk of hepatocellular carcinoma: A case-control study in Bangladesh

Collaborators (7)

Brygida Ślaska

Chandra S Pareek

Leyland Fraser

Hidesato Ogawa

Kamila Patrycja Liput

Piotr Poznański

Christopher Wardell

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