Hirofumi Kosuge

Project Assistant Professor

The Univeristy of Tokyo

Japan

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About

Hirofumi Kosuge is a Project Assistant Professor at The University of Tokyo, Japan. His research focuses on the role of PRELP in cell-cell adhesion, the blood-brain barrier, and bladder cancer, as well as biophysical characterization of protein interactions. Recent publications include studies on PRELP functions, its interactions with membrane proteins, and HPLC analysis of glycan structures.

Articles (7)

Year:

2025

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2021

Year:

2020

Collaborators (6)

Mandeep Sagoo

University College London

UNITED KINGDOM

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Makoto Nakakido

Lecturer

University of Tokyo

JAPAN

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Ryohei Sekido

Senior Lecturer

University of Portsmouth

UNITED KINGDOM

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Syuzo Kaneko

Laboratory Head

National Cancer Center

JAPAN

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Satoru Nagatoishi

Associate Professor

University of Tokyo

JAPAN

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Kouhei Tsumoto

JAPAN

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Hirofumi Kosuge

Research Interests

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Articles (7)

PRELP functions via multiple interactions with intrinsically weak affinity relying on ECM anchoring and remodeling.

Biophysical Characterization of the Contribution of the Fab Region to the IgG-FcγRIIIa Interaction

PRELP secreted from mural cells protects the function of blood brain barrier through regulation of endothelial cell-cell integrity

<i>PRELP</i> Regulates Cell–Cell Adhesion and EMT and Inhibits Retinoblastoma Progression

Repression of the PRELP gene is relieved by histone deacetylase inhibitors through acetylation of histone H2B lysine 5 in bladder cancer

Proteomic identification and validation of novel interactions of the putative tumor suppressor PRELP with membrane proteins including IGFI-R and p75NTR

Highly sensitive HPLC analysis and biophysical characterization of N‐glycans of IgG‐Fc domain in comparison between CHO and 293 cells using FcγRIIIa ligand

Collaborators (6)

Mandeep Sagoo

Makoto Nakakido

Ryohei Sekido

Syuzo Kaneko

Satoru Nagatoishi

Kouhei Tsumoto

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