Hiroki Kakuta

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Associate Professor

Okayama University

Japan

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About

Hiroki Kakuta is an Associate Professor at Okayama University in Japan. His research focuses on the development of innovative drug delivery systems and the study of retinoid X receptors, particularly in the context of oral immunotherapy and receptor visualization techniques. Recent articles authored by Professor Kakuta include investigations into ligand binding dynamics and the creation of fluorescent ligands for enhanced receptor analysis.

Recent Grants

Grant: Close

腫瘍部位におけるホウ素濃度の計測を可能とするBNCT用薬剤の創出

Open Date: 2019-04-01

Close Date: 2022-03-01

Articles (13)

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2025

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2020

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2020

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2020

Collaborators (2)

Shogo Nakano

Shizuoka University

JAPAN

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Masaharu Seno

Professor of Cancer Stem Cell Engineering

Okayama University

JAPAN

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Hiroki Kakuta

Research Interests

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Contact this professor

About

Recent Grants

Articles (13)

Preparation of PLGA Nanoparticles Co-Incorporated with Protein and Hydrophobic Drugs as a Formulation of Oral Immunotherapy

Simple Fluorescence Labeling Method Enables Detection of Intracellular Distribution and Expression Level of Retinoid X Receptors

Ligand Screening System for the RXRα Heterodimer Using the Fluorescence RXR Agonist CU-6PMN

Direct evaluation of polarity of the ligand binding pocket in retinoid X receptor using a fluorescent solvatochromic agonist

Teratogenicity and Fetal-Transfer Assessment of the Retinoid X Receptor Agonist Bexarotene

Increased Molecular Flexibility Widens the Gap between Ki and Kd values in Screening for Retinoid X Receptor Modulators

Creation of Fluorescent RXR Antagonists Based on CBTF-EE and Application to a Fluorescence Polarization Binding Assay

In Vivo Receptor Visualization and Evaluation of Receptor Occupancy with Positron Emission Tomography

Discovery of a “Gatekeeper” Antagonist that Blocks Entry Pathway to Retinoid X Receptors (RXRs) without Allosteric Ligand Inhibition in Permissive RXR Heterodimers

Fluorescence properties of retinoid X receptor antagonist NEt-SB

Convenient Retinoid X Receptor Binding Assay Based on Fluorescence Change of the Antagonist NEt-C343.

Paclitaxel and Sorafenib: The Effective Combination of Suppressing the Self-Renewal of Cancer Stem Cells

Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice

Collaborators (2)

Shogo Nakano

Masaharu Seno

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