Hiroshi Kimura

Professor

Tokyo Institute of Technology

Japan

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Hiroshi Kimura is a Professor at Tokyo Institute of Technology in Japan. His research focuses on transcription elongation dynamics, chromatin remodeling, and the molecular mechanisms of gene expression regulation. Recent publications highlight his work on adipogenesis, chromatin compartmentalization, and innovative approaches to nuclear import activity. His contributions to the field enhance the understanding of epigenetic modifications and their effects on cellular processes.

Articles (20)

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2025

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2023

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2022

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2022

Collaborators (21)

Yusuke Kishi

Associate Professor

University of Tokyo

JAPAN

Hiroshi Kimura

Research Interests

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Articles (20)

Iron‐Dependent JMJD1A‐Mediated Demethylation of H3K9me2 Regulates Gene Expression During Adipogenesis in a Spatial Genome Organization‐Dependent Manner

Structural insights into how DEK nucleosome binding facilitates H3K27 trimethylation in chromatin

Organization and Dynamics of Transcription Elongation Foci in Mouse Tissues.

Glucose-activated JMJD1A drives visceral adipogenesis via α-ketoglutarate-dependent chromatin remodeling.

Designer Catalyst-Enabled Regiodivergent Histone Acetylation.

The G9a histone methyltransferase represses osteoclastogenesis and bone resorption by regulating NFATc1 function

HMGA1 orchestrates chromatin compartmentalization and sequesters genes into 3D networks coordinating senescence heterogeneity

ISWI chromatin remodeling complexes recruit NSD2 and H3K36me2 in pericentromeric heterochromatin

Reconstruction of artificial nuclei with nuclear import activity in living mouse oocytes

Visualizing histone H4K20me1 in knock-in mice expressing the mCherry-tagged modification-specific intracellular antibody

Dense and Acidic Organelle-Targeted Visualization in Living Cells: Application of Viscosity-Responsive Fluorescence Utilizing Restricted Access to Minimum Energy Conical Intersection

Actin filaments accumulated in the nucleus remain in the vicinity of condensing chromosomes in the zebrafish early embryo

Organization of transcription and 3D genome as revealed by live-cell imaging

Live-cell tracking of γ-H2AX kinetics reveals the distinct modes of ATM and DNA-PK in the immediate response to DNA damage

Transient Methionine Deprivation Triggers Histone Modification and Potentiates Differentiation of Induced Pluripotent Stem Cells

Two Onnamide Analogs from the Marine Sponge Theonella conica: Evaluation of Geometric Effects in the Polyene Systems on Biological Activity

Nanog organizes transcription bodies

The role of H3K9me3 in oral squamous cell carcinoma

STREAMING-tag system reveals spatiotemporal relationships between transcriptional regulatory factors and transcriptional activity

A Drosophila toolkit for HA-tagged proteins unveils a block in autophagy flux in the last instar larval fat body

Collaborators (21)

Yusuke Kishi

Timothy J. Stasevich

Motomu Kanai

Yuko Sato

Makoto Tachibana

Kohei Kawaguchi

Tokuko Haraguchi

Junya Adachi

Nadine Vastenhouw

Chaoran Yang

Kazushi Kinbara

takeshi inagaki

Yoshimasa Takizawa

Hiroshi Ochiai

Hidenori Nishihara

Yasushi Hiraoka

Kohei Sato

Akira Nifuji

Yasuyuki Ohkawa

Ning Zhao

Hiroka Sugai

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