Hiroyuki Kamiya

Professor

Hiroshima University

Japan

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Professor Hiroyuki Kamiya is a faculty member at Hiroshima University, Japan. His research focuses on DNA mutations and repair mechanisms, particularly in relation to oxidized nucleotides and their effects on genetic stability. Recent publications include studies on the visualization of oxidized guanine in living cells and the development of high-throughput mutagenesis assays.

Articles (14)

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2024

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2024

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2024

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2024

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2022

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2022

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2022

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2022

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2022

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2021

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2021

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2021

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2020

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2020

Collaborators (2)

Yasuo Komatsu

National Institute of Advanced Industrial Science and Technology (AIST)

JAPAN

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Hidehiko Kawai

Associate Professor

Hiroshima University

JAPAN

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Hiroyuki Kamiya

Research Interests

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Articles (14)

Visualization of oxidized guanine nucleotides accumulation in living cells with split MutT

Correction of substitution, deletion, and insertion mutations by 5′-tailed duplexes

Untargeted Mutation Triggered by Ribonucleoside Embedded in DNA

Action-at-a-distance mutations induced by 8-oxo-7,8-dihydroguanine are dependent on APOBEC3

Easily-controllable, helper phage-free single-stranded phagemid production system

Development of a versatile high-throughput mutagenesis assay with multiplexed short-read NGS using DNA-barcoded supF shuttle vector library amplified in E. coli

Biased distribution of action-at-a-distance mutations by 8-oxo-7,8-dihydroguanine

Correction of monomeric enhanced green fluorescent protein (mEGFP) gene by short 5′-tailed duplexes

Paradoxical role of the major DNA repair protein, OGG1, in action-at-a-distance mutation induction by 8-oxo-7,8-dihydroguanine

Action-at-a-distance mutations at 5′-GpA-3′ sites induced by oxidised guanine in WRN-knockdown cells

Gene correction by 5′-tailed duplexes with short editor oligodeoxyribonucleotides

Similar frequency and signature of untargeted substitutions induced by abasic site analog under reduced human ape1 conditions

Conventional plasmid DNAs with a CpG-containing backbone achieve durable transgene expression in mouse liver

High-throughput analysis of DNA repair in microplates towards identification of inhibitors

Collaborators (2)

Yasuo Komatsu

Hidehiko Kawai

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