Hisashi Doi

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Specially Appointed Professor

Osaka University

Japan

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About

Hisashi Doi is a Specially Appointed Professor at Osaka Metropolitan University, Japan. His research primarily focuses on positron emission tomography (PET) imaging techniques, particularly in the evaluation of neuroinflammation and amino acid transporters. Recent publications include studies on TRPV1-targeted PET imaging and the assessment of radiotherapy responses using various PET tracers.

Recent Grants

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Development of SN-38 derivatives with antitumor activity toward theranostics

Open Date: 2020-04-01

Close Date: 2023-03-31

Grant: Close

General A, research grant for Cancer Research from Foundation for Promotion of Cancer Research

Open Date: 2018-04-01

Close Date: 2019-03-01

Grant: Close

Consignment research for measurement of pharmacokinetics of nucleic acid medicine from Fukuoka BioValley Project

Open Date: 2018-04-01

Close Date: 2020-03-01

Grant: Close

Study on transporter activities and its interactions between organ systems in chronic kidney disease by positron emission tomography

Open Date: 2017-04-01

Close Date: 2019-03-31

Grant: Close

Grant-in-Aid from Hyogo Science and Technology Association

Open Date: 2016-04-01

Close Date: 2017-03-01

Articles (16)

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2021

Collaborators (2)

Mieko Tsuji

Gifu Pharmaceutical University

JAPAN

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Takashi Niwa

Professor

Kyushu University

JAPAN

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Hisashi Doi

Research Interests

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About

Recent Grants

Articles (16)

Transient receptor potential cation channel subfamily V member 1 (TRPV1) targeted PET imaging

Regional neuroinflammation induced by peripheral infection contributes to fatigue-like symptoms: a [18F]DPA-714 positron emission tomography study in rats

In vitro evaluation of (S)-2-amino-3-[3-(2-18F-fluoroethoxy)-4-iodophenyl]-2-methylpropanoic acid (18F-FIMP) as a positron emission tomography probe for imaging amino acid transporters

Characteristic Evaluation of a <sup>11</sup>C-Labeled Leucine Analog, <scp>l</scp>-α-[5-<sup>11</sup>C]methylleucine, as a Tracer for Brain Tumor Imaging by Positron Emission Tomography

Comparison of [18F]FIMP, [11C]MET, and [18F]FDG PET for early-phase assessment of radiotherapy response

<i>N</i>-Methylamide-structured SB366791 derivatives with high TRPV1 antagonistic activity: toward PET radiotracers to visualize TRPV1

Clinical evaluation of [<sup>18</sup>F]pitavastatin for quantitative analysis of hepatobiliary transporter activity.

[<sup>18</sup>F]DPA-714 PET imaging for the quantitative evaluation of early spatiotemporal changes of neuroinflammation in rat brain following status epilepticus.

First-in-human assessment of the novel LAT1 targeting PET probe <sup>18</sup>F-FIMP.

<i>N</i>-Methylamide-structured SB366791 derivatives with high TRPV1 antagonistic activity: toward PET radiotracers to visualize TRPV1

Synthesis and Preclinical Evaluation of <sup>18</sup>F-Labeled Ketoprofen Methyl Esters for Cyclooxygenase-1 Imaging in Neuroinflammation.

Clinical evaluation of [<SUP>18</SUP>F]pitavastatin for quantitative analysis of hepatobiliary transporter activity

PET imaging of brain aromatase in humans and rhesus monkeys by 11C-labeled cetrozole analogs

Pd0‐Mediated Cross‐Coupling of [11C]Methyl Iodide with Carboxysilane for Synthesis of [11C]Acetic Acid and Its Active Esters: 11C‐Acetylation of Small, Medium, and Large Molecules

Synthesis of L‐[5‐11C]Leucine and L‐alfa‐[5‐11C]Methylleucine via Pd0‐mediated 11C‐Methylation and Microfluidic Hydrogenation: Potentiality of Leucine PET Probes for Tumor Imaging

PET imaging of 11C-labeled thiamine tetrahydrofurfuryl disulfide, vitamin B1 derivative: First-in-human study

Collaborators (2)

Mieko Tsuji

Takashi Niwa

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