Hong Lu

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Associate Professor (Regular Title Series with Tenure)

University of Kentucky

United States

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About

Dr. Hong Lu is an Associate Professor at the University of Kentucky, USA. His research focuses on cardiovascular and metabolic diseases, particularly in relation to aortic aneurysms and therapeutic targets. Recent articles authored by Dr. Lu examine the implications of angiotensin II in hypercholesterolemic conditions, as well as the complexities of thoracic aortopathy and its treatment challenges. He is also actively engaged in advancing career support for women faculty in science and academic medicine.

Recent Grants

Grant: Open

Determinants of Aorta Heterogeneity

Open Date: 2021-06-01

Close Date: 2028-05-01

Grant: Close

Atherosclerosis Mechanisms: Angiotensin II production and action

Open Date: 2018-05-01

Close Date: 2022-03-31

Articles (19)

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2025

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2022

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2022

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2022

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2022

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2022

Collaborators (13)

Suellen D'Arc Oliveira

Assistant Professor

University of Chicago

UNITED STATES

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ingrid garrelds

Erasmus University Rotterdam

NETHERLANDS

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Delphine Gomez

Assistant Professor

University of Pittsburgh

UNITED STATES

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Deborah Howatt

University of Kentucky

UNITED STATES

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Hisashi Sawada

University of Kentucky

UNITED STATES

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Gabrielle Fredman

UNITED STATES

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Congqing Wu

Assistant Professor

University of Kentucky

UNITED STATES

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Zhen Bouman-Chen

City of Hope

UNITED STATES

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Mary Sheppard

University of Kentucky College of Medicine

UNITED STATES

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Mabruka Alfaidi

Assistant Professor of Medicine

LSU Health Shreveport

UNITED STATES

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Dien Ye

Erasmus University Rotterdam

NETHERLANDS

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Scott Gordon

Assistant Professor

University of Kentucky

UNITED STATES

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John Curci

Chief of Vascular and Endovascular Surgery

VA Tennessee Valley Healthcare System

UNITED STATES

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Hong Lu

Research Interests

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About

Recent Grants

Articles (19)

Thermoneutrality Does Not Affect Angiotensin II–Induced Aortic Aneurysms in Hypercholesterolemic Mice

β-aminopropionitrile-induced thoracic aortopathy is refractory to cilostazol and sildenafil in mice

Is IDOL an Ideal Target for Treating Atherosclerosis?

Institutional Support for the Career Advancement of Women Faculty in Science and Academic Medicine: Successes, Challenges, and Future Directions

Angiotensinogen as a Therapeutic Target for Cardiovascular and Metabolic Diseases

Small AAAs: Recommendations for Rodent Model Research for the Identification of Novel Therapeutics

Research Advances in Abdominal Aortic Aneurysms: Triglyceride-Rich Lipoproteins as a Therapeutic Target

Abdominal aortic aneurysms and platelets: infiltration, inflammation, and elastin disintegration

Divergent Roles of Matrix Metalloproteinase 12 in Abdominal Aortic Aneurysms

Angiotensinogen in Sex and Hypertension

Aortic Stress Activates an Adaptive Program in Thoracic Aortic Smooth Muscle Cells That Maintains Aortic Strength and Protects Against Aneurysm and Dissection in Mice

Association of NOTCH3 With Elastic Fiber Dispersion in the Infrarenal Abdominal Aorta of Cynomolgus Monkeys

Inhibition of the Renin-Angiotensin System Fails to Suppress β-Aminopropionitrile–Induced Thoracic Aortopathy in Mice—Brief Report

Conventional Vasopressor and Vasopressor-Sparing Strategies to Counteract the Blood Pressure-Lowering Effect of Small Interfering RNA Targeting Angiotensinogen

Aortic Aneurysm and Dissection: Heterogeneity and Molecular Mechanisms

Embryonic Heterogeneity of Smooth Muscle Cells in the Complex Mechanisms of Thoracic Aortic Aneurysms

Expression of a PCSK9 Gain-of-Function Mutation in C57BL/6J Mice to Facilitate Angiotensin II-Induced AAAs

A mini-review on quantification of atherosclerosis in hypercholesterolemic mice

Dennd5b-Deficient Mice are Resistant to PCSK9-Induced Hypercholesterolemia and Diet-Induced Hepatic Steatosis

Collaborators (13)

Suellen D'Arc Oliveira

ingrid garrelds

Delphine Gomez

Deborah Howatt

Hisashi Sawada

Gabrielle Fredman

Congqing Wu

Zhen Bouman-Chen

Mary Sheppard

Mabruka Alfaidi

Dien Ye

Scott Gordon

John Curci

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