Hong Wen

Associate Professor

Van Andel Institute

United States

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Hong Wen is an Associate Professor at the Van Andel Research Institute in the United States. His research focuses on the molecular mechanisms underlying cancer and kidney development, as evidenced by his recent articles exploring mutations in ENL and KAT8, as well as the development of the Bioconductor package bamSliceR for variant analysis. His work contributes to a deeper understanding of epigenetic regulation and cellular vulnerabilities in cancer biology.

Articles (6)

Year:

2025

Year:

2025

Year:

2024

Year:

2024

Year:

2024

Year:

2023

Collaborators (4)

Lisa Turner

Van Andel Institute

UNITED STATES

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Xiaobing Shi

Professor

Van Andel Institute

UNITED STATES

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Tim Triche

Associate Professor

Van Andel Institute

UNITED STATES

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Tinghai Xu

Assistant Professor

Saint Louis University

UNITED STATES

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Hong Wen

Research Interests

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Articles (6)

Expression of ENL YEATS domain tumor mutations in nephrogenic or stromal lineage impairs kidney development

A multivalent engagement of ENL with MOZ

Hotspot Cancer Mutation Impairs KAT8-mediated Nucleosomal Histone Acetylation

The Tudor-knot Domain of KAT5 Regulates Nucleosomal Substrate Acetylation

bamSliceR: a Bioconductor package for rapid, cross-cohort variant and allelic bias analysis

TAZ2 truncation confers overactivation of p300 and cellular vulnerability to HDAC inhibition

Collaborators (4)

Lisa Turner

Xiaobing Shi

Tim Triche

Tinghai Xu

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