Hsun Ku

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Associate Professor

Beckman Research Institute, City of Hope

United States

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About

Dr. Hsun Ku is an Associate Professor at the Beckman Research Institute, City of Hope in the United States. His research focuses on the characterization and functionality of pancreatic islet cells, as well as the mechanisms influencing pancreatic regeneration and transplant success. His recent publications explore topics such as single-cell analysis, extracellular matrix signaling, and methods for culturing pancreatic endocrine cells.

Recent Grants

Grant: Close

EX VIVO DIFFERENTIATION AND EXPANSION OF ADULT PANCREATIC COLONY-FORMING UNITS

Open Date: 2014-04-01

Close Date: 2019-03-31

Grant: Close

Insulin-Expressing Colony Forming Progenitors

Open Date: 2008-08-01

Close Date: 2014-06-30

Grant: Close

Endocrine Pancreas from Sox17+ Endoderm Progenitors

Open Date: 2006-04-01

Close Date: 2009-03-31

Grant: Close

Generation of Transplantable Pancreatic Beta Cells from Murine Embryonic Stem Cells

Open Date: 2004-03-01

Close Date: 2007-02-28

Grant: Close

Isolation and Characterization of Murine Adult Pancreatic Endocrine Stem Cells

Open Date: 2001-10-01

Close Date: 2002-09-30

Articles (12)

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2024

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2024

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2023

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2023

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2023

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2021

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2020

Collaborators (2)

Janine Quijano

Assistant Research Professor

City Of Hope National Medical Center

UNITED STATES

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Eunjin Oh

Associate Research Professor

City Of Hope National Medical Center

UNITED STATES

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Hsun Ku

Research Interests

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About

Recent Grants

Articles (12)

Characterization of Human Pancreatic Islet Cells Using a Single-Cell Western Blot Platform

4S-fluorination of ProB29 in insulin lispro slows fibril formation

Activation of ductal progenitor-like cells from adult human pancreas requires extracellular matrix protein signaling

Biological hypoxia in pre-transplant human pancreatic islets induces transplant failure in diabetic mice

Physiomimetic Fluidic Culture Platform on Microwell-Patterned Porous Collagen Scaffold for Human Pancreatic Islets

Rare, Tightly-Bound, Multi-Cellular Clusters in the Pancreatic Ducts of Adult Mice Function Like Progenitor Cells and Survive and Proliferate After Acinar Cell Injury

Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for β-Cell Function During Aging

Incorporation of Aliphatic Proline Residues into Recombinantly Produced Insulin

A matrigel-free method for culture of pancreatic endocrine-like cells in defined protein-based hydrogels

Methylcellulose colony assay and single-cell micro-manipulation reveal progenitor-like cells in adult human pancreatic ducts

Towards organoid culture without Matrigel

Erratum: A GLIS3-CD133-WNT-signaling axis regulates the self-renewal of adult murine pancreatic progenitor-like cells in colonies and organoids (Journal of Biological Chemistry DOI: 10.1074/jbc.RA118.002818)

Collaborators (2)

Janine Quijano

Eunjin Oh

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