Huan Xie

Professor

Texas Southern University

United States

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About

Huan Xie is a Professor at Texas Southern University, located in the United States. His research areas include drug metabolism and pharmacokinetics, with a focus on therapeutic agents for treating various cancers, including triple-negative breast cancer and glioblastoma. He has authored several recent articles that explore the characterization of novel inhibitors and the pharmacokinetic behaviors of drug formulations.

Articles (16)

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2025

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2022

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2022

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2022

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2021

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2021

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University of Texas Health Science Center at San Antonio

UNITED STATES

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Huan Xie

Research Interests

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Articles (16)

The Discovery and Characterization of HBS-101, a Novel Inhibitor of Midkine, as a Therapeutic Agent for the Treatment of Triple-Negative Breast Cancer

Drug Metabolism and Pharmacokinetic Evaluation of a Novel RNase H2 Inhibitor for the Treatment of Triple-Negative Breast Cancer

Clay Attenuates Diarrhea Induced by Fat in a Mouse Model

Fragmentation Patterns of Phenolic C-Glycosides in Mass Spectrometry Analysis

Impact of Species and Tissue Differences on In Vitro Glucuronidation of Diclofenac

Species Differences in Ezetimibe Glucuronidation

Preclinical Development of Brain Permeable ERβ Agonist for the Treatment of Glioblastoma

Metabolite Identification of a Novel Anti-Leishmanial Agent OJT007 in Rat Liver Microsomes Using LC-MS/MS

Pharmacokinetic behaviors of soft nanoparticulate formulations of chemotherapeutics.

Accurate Mass Identification of an Interfering Water Adduct and Strategies in Development and Validation of an LC-MS/MS Method for Quantification of MPI8, a Potent SARS-CoV-2 Main Protease Inhibitor, in Rat Plasma in Pharmacokinetic Studies.

Surfactant Mediated Accelerated and Discriminatory In Vitro Drug Release Method for PLGA Nanoparticles of Poorly Water-Soluble Drug

Development and Validation of an LC–MS/MS Method for AC1LPSZG and Pharmacokinetics Application in Rats

Determination of Oxaliplatin by a UHPLC-MS/MS Method: Application to Pharmacokinetics and Tongue Tissue Distribution Studies in Rats

Pharmacokinetic Model Analysis of Supralingual, Oral and Intravenous Deliveries of Mycophenolic Acid

In vitro dissolution considerations associated with nano drug delivery systems

Development and Validation of a Sensitive, Specific and Reproducible UPLC-MS/MS Method for the Quantification of OJT007, A Novel Anti-Leishmanial Agent: Application to a Pharmacokinetic Study

Collaborators (7)

John Sanchez

song gao

Suryavathi Viswanadhapalli

Robert Tsai

Xiaohua Liu

Dong Liang

Gangadhara Reddy Sareddy

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