Huimin Zhao

Professor

University of Illinois at Urbana-Champaign

United States

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About

Huimin Zhao is a Professor at the University of Illinois Urbana-Champaign, USA. His research areas include enzymatic pathways for peptide modification, evolutionary mechanisms of enoyl isomerases, and artificial intelligence applications in enzyme engineering. Recent publications highlight advancements in mitochondrial metabolism, organic acid production, and the exploration of natural products and gene expression systems.

Articles (30)

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2023

Collaborators (9)

Dongping Zhong

Ohio State University

UNITED STATES

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David Gilbert

Professor

San Diego Biomedical Research Institute

UNITED STATES

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Jonathan Chekan

Assistant Professor

University of North Carolina at Greensboro

UNITED STATES

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Shravan Dommaraju

Vanderbilt University

UNITED STATES

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Guangde Jiang

Assistant Professor

Wayne State University

UNITED STATES

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Piyush Jain

Assistant Professor

University of Florida

UNITED STATES

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Aashutosh Boob

University of Illinois Urbana–Champaign

UNITED STATES

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Chao Yang

Deutsches Elektronen-Synchrotron DESY

GERMANY

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Tao Pan

University of Chicago

UNITED STATES

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Huimin Zhao

Research Interests

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About

Articles (30)

A Versatile Enzymatic Pathway for Modification of Peptide C-Termini

A Unified Mechanism Reveals the Evolutionary Origin of Enoyl Isomerases

AccFG: Accurate Functional Group Extraction and Molecular Structure Comparison

Decompartmentalization of the yeast mitochondrial metabolism to improve chemical production in Issatchenkia orientalis

Discovery and Characterization of Oxazolismycin, an Oxazole-Containing Natural Product with an Atypical Loading Mechanism

A generalized platform for artificial intelligence-powered autonomous enzyme engineering

Photoenzymatic stereoablative enantioconvergence of γ-chiral oximes via hydrogen atom transfer

Design of diverse, functional mitochondrial targeting sequences across eukaryotic organisms using variational autoencoder

Discovery, characterization, and application of chromosomal integration sites for stable heterologous gene expression in Rhodotorula toruloides

Issatchenkia orientalis as a platform organism for cost-effective production of organic acids

Multifunctional Glucose Dehydrogenase Enabled Synthesis of Chiral-Bridged Bicyclic Nitrogen Heterocycles

Photoenzymatic Asymmetric Hydroamination for Chiral Alkyl Amine Synthesis

Prokaryotic RNA N1-Methyladenosine Erasers Maintain tRNA m1A Modification Levels in Streptomyces venezuelae

Biochemical Investigation and Engineering of a Tardigrade X Family DNA Polymerase for Template-Independent DNA Synthesis

Non-modular fatty acid synthases yield distinct N-terminal acylation in ribosomal peptides

Asymmetric photoenzymatic incorporation of fluorinated motifs into olefins

Enterolyin S, a Polythiazole‐containing Hemolytic Peptide from Enterococcus caccae

Harnessing noncanonical crRNA for highly efficient genome editing

Self-Buffering system for Cost-Effective production of lactic acid from glucose and xylose using Acid-Tolerant Issatchenkia orientalis

CRISPR-COPIES: an in silico platform for discovery of neutral integration sites for CRISPR/Cas-facilitated gene integration

SHIELD: a platform for high-throughput screening of barrier-type DNA elements in human cells

To cut or not to cut: Next-generation genome editors for precision genome engineering

Incorporation of noncanonical base Z yields modified mRNA with minimal immunogenicity and improved translational capacity in mammalian cells

Machine Learning-Enabled Genome Mining and Bioactivity Prediction of Natural Products

In vitro continuous protein evolution empowered by machine learning and automation

Photoenzymatic enantioselective intermolecular radical hydroamination

A landing pad system for multicopy gene integration in Issatchenkia orientalis

Further Characterization of Fungal Halogenase RadH and Its Homologs

Ene Reductase Enabled Intramolecular β‐C−H Functionalization of Substituted Cyclohexanones for Efficient Synthesis of Bridged Bicyclic Nitrogen Scaffolds

Ene Reductase Enabled Intramolecular β‐C−H Functionalization of Substituted Cyclohexanones for Efficient Synthesis of Bridged Bicyclic Nitrogen Scaffolds

Collaborators (9)

Dongping Zhong

David Gilbert

Jonathan Chekan

Shravan Dommaraju

Guangde Jiang

Piyush Jain

Aashutosh Boob

Chao Yang

Tao Pan

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