Hyonchol Jang

Senior Scientist, associate professor

National Cancer Center

South Korea

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About

Hyonchol Jang is a Senior Scientist and Associate Professor at the National Cancer Center in South Korea. His research focuses on protein-protein interactions at mitochondria-associated ER membranes, cancer metabolism, and the molecular mechanisms underlying cancer stem cell characteristics. Recent publications highlight his work on tumor biology, including studies on PD-L1 expression and the role of cholesterol synthesis in cancer cell behavior.

Articles (15)

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2025

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2024

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2024

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2024

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2023

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2022

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2022

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2021

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2021

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2021

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2021

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2021

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2020

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2020

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2020

Collaborators (8)

Jong In Yook

Professor

Yonsei University College of Dentistry

SOUTH KOREA

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HYUN-WOO SHIN

Seoul National University College of Medicine

SOUTH KOREA

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Daekee Lee

Professor

Ewha Womans University

SOUTH KOREA

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John R. Engen

Northeastern University

UNITED STATES

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Hyun Seung Ban

Korea Research Institute of Bioscience and Biotechnology

SOUTH KOREA

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Ho Lee

Professor

SOUTH KOREA

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Soo-Youl Kim

Head

National Cancer Center

SOUTH KOREA

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BYUNG IL LEE

Principal Investigator, Chief Scientist, Professor (Tenured)

National Cancer Center Research Institute

SOUTH KOREA

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Hyonchol Jang

Research Interests

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Articles (15)

Crystal structure of Fis1 and Bap31 provides information on protein-protein interactions at mitochondria-associated ER membranes

The serine phosphorylations in the IRS-1 PIR domain abrogate IRS-1 and IR interaction

Activatable near-infrared fluorescence probe for real-time imaging of PD-L1 expression in tumors.

SOX2 Expression Does Not Guarantee Cancer Stem Cell-like Characteristics in Lung Adenocarcinoma

Glucose Deprivation Induces Cancer Cell Death through Failure of ROS Regulation

BMS794833 inhibits macrophage efferocytosis by directly binding to MERTK and inhibiting its activity

Cholesterol Synthesis Is Important for Breast Cancer Cell Tumor Sphere Formation and Invasion

PGC1α Loss Promotes Lung Cancer Metastasis through Epithelial-Mesenchymal Transition

Phospholipid transfer function of PTPIP51 at mitochondria-associated ER membranes

Reply to Krupenko et al., Comment on “Lee et al. The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung Cancer <i>Cancers</i> 2020, <i>12</i>, 1382”

Overall survival of pancreatic ductal adenocarcinoma is doubled by <i>Aldh7a1</i> deletion in the KPC mouse.

FAM188B Downregulation Sensitizes Lung Cancer Cells to Anoikis via EGFR Downregulation and Inhibits Tumor Metastasis In Vivo

Oxoglutarate Carrier Inhibition Reduced Melanoma Growth and Invasion by Reducing ATP Production

Crystal Structure of the Kinase Domain of MerTK in Complex with AZD7762 Provides Clues for Structure-Based Drug Development

SEZ6L2 Is an Important Regulator of Drug-Resistant Cells and Tumor Spheroid Cells in Lung Adenocarcinoma

Collaborators (8)

Jong In Yook

HYUN-WOO SHIN

Daekee Lee

John R. Engen

Hyun Seung Ban

Ho Lee

Soo-Youl Kim

BYUNG IL LEE

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