Hyun-Sung Lee

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Associate Professor

Baylor College of Medicine

United States

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About

Hyun-Sung Lee is an Associate Professor at Baylor College of Medicine in the United States. His research focuses on the immune environment in cancer, particularly in lung and pancreatic cancers, as well as the molecular mechanisms underlying tumor promotion and immune responses. Recent publications explore topics such as the role of MAGE-A4 in non-small cell lung cancer, racial disparities in pancreatic cancer immune microenvironments, and therapeutic strategies for enhancing treatment sensitivity in malignancies.

Recent Grants

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Spatial Profiling of Tumor-Immune Microenvironment by Multiplexed Single- Cell Imaging Mass Cytometry

Open Date: 2020-02-19

Close Date:

Articles (16)

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2025

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2020

Collaborators (11)

Sung Yun Jung

Associate Professor

Baylor College of Medicine

UNITED STATES

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Heather Cordell

Professor of Statistical Genetics

Newcastle University

UNITED KINGDOM

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Myung-Shin Lee

Professor

Eulji University School of Medicine

SOUTH KOREA

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Yong Sun Lee

Professor

National Cancer Center

SOUTH KOREA

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Ju-Seog Lee

Professor

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Wendong Yu

Associate Professor

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Xiang Zhang

Professor, William T. Butler Endowed Chair, Interim Director

Baylor College of Medicine

UNITED STATES

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Xiaoyong Bao

University of Texas Medical Branch

UNITED STATES

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Suzanne Fuqua

Professor

Baylor College of Medicine

UNITED STATES

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Catherine Zhu

Baylor College of Medicine

UNITED STATES

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Aarthi Pugazenthi

Baylor College of Medicine

UNITED STATES

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Hyun-Sung Lee

Research Interests

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About

Recent Grants

Articles (16)

MAGE-A4 Induces Non-Small Cell Lung Cancer and Tumor-Promoting Plasma Cell Accumulation

Skewed adaptive immune responses are involved in alpha-1 antitrypsin deficiency emphysema

The immune sensitivity caused by DUSP11, an RNA 5′-end maturation phosphatase, is adjusted by a human non-coding RNA, nc886

Tumor Immune Microenvironment Differences Associated With Racial Disparities in Pancreatic Cancer

Incongruity between T cell receptor recognition of breast cancer hotspot mutations ESR1 Y537S and D538G following exogenous peptide loading versus endogenous antigen processing

Clonal gene signatures predict prognosis in mesothelioma and lung adenocarcinoma

Intratumoral immune triads are required for immunotherapy-mediated elimination of solid tumors

Sphingosine-1-Phosphate Inhibition Increases Endoplasmic Reticulum Stress to Enhance Oxaliplatin Sensitivity in Pancreatic Cancer

Translational and oncologic significance of tertiary lymphoid structures in pancreatic adenocarcinoma

Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis

A Phase II Window of Opportunity Study of Neoadjuvant PD-L1 versus PD-L1 plus CTLA-4 Blockade for Patients with Malignant Pleural Mesothelioma

Therapeutic Targeting of Macrophage Plasticity Remodels the Tumor-Immune Microenvironment

Activation of Adaptive and Innate Immune Cells via Localized IL2 Cytokine Factories Eradicates Mesothelioma Tumors

A combination of intrinsic and extrinsic features improves prognostic prediction in malignant pleural mesothelioma

Nc886, a Novel Suppressor of the Type I Interferon Response Upon Pathogen Intrusion

A Regulatory Noncoding RNA, nc886, Suppresses Esophageal Cancer by Inhibiting the AKT Pathway and Cell Cycle Progression

Collaborators (11)

Sung Yun Jung

Heather Cordell

Myung-Shin Lee

Yong Sun Lee

Ju-Seog Lee

Wendong Yu

Xiang Zhang

Xiaoyong Bao

Suzanne Fuqua

Catherine Zhu

Aarthi Pugazenthi

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