Ian Tietjen

Assistant Professor

The Wistar Institute

United States

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Ian Tietjen is an Assistant Professor at The Wistar Institute in the United States. His research focuses on antiviral mechanisms and the development of inhibitors targeting various viruses, including SARS-CoV-2 and influenza A. Recent articles highlight his work in bioassay-guided isolation of viral entry inhibitors, as well as the synthesis and evaluation of novel molecules for therapeutic applications against viral infections.

Articles (10)

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2025

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2025

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2025

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2024

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2024

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2024

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2023

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2023

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2023

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2023

Collaborators (3)

Toshitha Kannan

The Wistar Institute

UNITED STATES

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Rohan Davis

Research Leader / Associate Professor

Griffith University

AUSTRALIA

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Robin B. Gasser

Redmond Barry Distinguished Professor

University of Melbourne

AUSTRALIA

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Ian Tietjen

Research Interests

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Articles (10)

Bioassay‐guided Isolation of SARS‐CoV‐2 Viral Entry Inhibitors From the Brown Algae Lobophora variegata Identifies Fucoxanthin as a Selective ACE‐2/Spike Inhibitor

Antiviral mechanisms and preclinical evaluation of amantadine analogs that continue to inhibit influenza A viruses with M2S31N-based drug resistance

A high-throughput, microplate reader-based method to monitor in vitro HIV latency reversal in the absence of flow cytometry

Design of novel and highly selective SARS-CoV-2 main protease inhibitors

Design, synthesis, and biochemical and computational screening of novel oxindole derivatives as inhibitors of Aurora A kinase and SARS-CoV-2 spike/host ACE2 interaction

Synthesis, SARS-CoV-2 main protease inhibition, molecular docking and in silico ADME studies of furanochromene-quinoline hydrazone derivatives

Using a Bioactive Eremophila-Derived Serrulatane Scaffold to Generate a Unique Carbamate Library for Anti-infective Evaluations

The Natural Stilbenoid (-)-Hopeaphenol Inhibits HIV Transcription by Targeting Both PKC and NF-κB Signaling and Cyclin-Dependent Kinase 9.

An ethnopharmacological survey of medicinal plants traditionally used by the BaKalanga people of the Tutume subdistrict in Central Botswana to manage HIV/AIDS, HIV-associated conditions, and other health conditions

Thorectidiol A Isolated from the Marine Sponge <i>Dactylospongia elegans</i> Disrupts Interactions of the SARS-CoV-2 Spike Receptor Binding Domain with the Host ACE2 Receptor.

Collaborators (3)

Toshitha Kannan

Rohan Davis

Robin B. Gasser

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