Ichiro Misumi

Assistant Professor

University of North Carolina at Chapel Hill

United States

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About

Ichiro Misumi is an Assistant Professor at the University of North Carolina at Chapel Hill, USA. His research focuses on virology and immunology, particularly in understanding hepatitis A virus interactions with host immune responses and mechanisms of liver injury. Recent articles authored by Professor Misumi explore the roles of natural killer cells, noncanonical poly(A) polymerases, and various therapeutic agents against hepatitis A virus infection.

Articles (11)

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2025

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2025

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2025

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2024

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2024

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2023

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2022

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2021

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2021

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2021

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2020

Collaborators (4)

Helen Lazear

Associate Professor

University of North Carolina

UNITED STATES

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Ewelina Kaluzna

Institute of Bioorganic Chemistry Polish Academy of Sciences

POLAND

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Jason Whitmire

Professor

University of North Carolina at Chapel Hill

UNITED STATES

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YOU LI

Research Assistant Professor

UNITED STATES

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Ichiro Misumi

Research Interests

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Articles (11)

Natural killer cells and IFN-γ protect against liver injury during HAV infection in mice

Noncanonical Poly(A) Polymerase TENT4 Drives Expression of Subgenomic Hepatitis A Virus RNAs in Infected Cells

Hepato-selective dihydroquinolizinones active against hepatitis A virus in vitro and in vivo

Interferon lambda restricts herpes simplex virus skin disease by suppressing neutrophil-mediated pathology

Hepatovirus translation requires PDGFA-associated protein 1, an eIF4E-binding protein regulating endoplasmic reticulum stress responses

Viral protease cleavage of MAVS in genetically modified mice with hepatitis A virus infection

The ZCCHC14/TENT4 complex is required for hepatitis A virus RNA synthesis

IRF3-mediated pathogenicity in a murine model of human hepatitis A

Iminosugar glucosidase inhibitors reduce hepatic inflammation in hepatitis a virus-infected Ifnar1<sup>2/2</sup> mice

T cells protect against hepatitis A virus infection and limit infection-induced liver injury

Gangliosides are essential endosomal receptors for quasi-enveloped and naked hepatitis A virus.

Collaborators (4)

Helen Lazear

Ewelina Kaluzna

Jason Whitmire

YOU LI

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